Rzayev Turkay, Gokce Kubra, Gucyetmez Safak, Bozkurt Suheyla, Dagcinar Adnan, Tokuc Gulnur, Yaman Akan, Bilgen Hulya, Ozek Eren
Division of Neonatology, Department of Pediatrics, Marmara University Faculty of Medicine, İstanbul, Turkey.
Department of Pathology, Marmara University Faculty of Medicine, İstanbul, Turkey.
Fetal Pediatr Pathol. 2022 Aug;41(4):665-669. doi: 10.1080/15513815.2021.1913536. Epub 2021 Apr 19.
In recent years, with the widespread use of assisted reproductive technologies, questions have arisen regarding the possible relationship between these infertile parents with assisted conception procedures and childhood cancers. We present a 23-day-old newborn conceived by in vitro fertilization (IVF) with a 53 × 46 × 38 mm intracranial mass detected by magnetic resonance imaging on the 15th postnatal day. The mass, removed on 23rd postnatal day, was an Atypical Teratoid Rhabdoid Tumor (ATRT), WHO grade 4. As far as we know, this is the only neonatally detected ATRT. Further studies are needed to investigate whether there is a causal relationship between IVF and childhood cancers.
近年来，随着辅助生殖技术的广泛应用，关于这些通过辅助受孕程序的不孕父母与儿童癌症之间可能存在的关系出现了一些问题。我们报告一例23日龄的新生儿，其通过体外受精（IVF）受孕，在出生后第15天经磁共振成像检测出颅内有一个53×46×38毫米的肿块。该肿块于出生后第23天切除，是一个非典型畸胎样横纹肌样瘤（ATRT），世界卫生组织分级为4级。据我们所知，这是唯一一例在新生儿期检测到的ATRT。需要进一步研究来调查IVF与儿童癌症之间是否存在因果关系。
