体外受精受孕婴儿患非典型畸胎样/横纹肌样瘤。
Atypical teratoid/rhabdoid tumor in an infant conceived by in vitro fertilization.
作者信息
Cecen Emre, Gunes Dilek, Uysal Kamer Mutafoglu, Yuceer Nurullah, Ozer Erdener
机构信息
Department of Pediatric Oncology, Adnan Menderes University School of Medicine, Aydin 09100, Turkey.
出版信息
Childs Nerv Syst. 2010 Feb;26(2):263-6. doi: 10.1007/s00381-009-1005-5. Epub 2009 Nov 24.
BACKGROUND
Atypical teratoid/rhabdoid tumor (ATsRT) is a rare tumor and extremely aggressive embryonal neoplasm of the central nervous system. Brain tumors in infant are suggestive of some oncogenic prenatal factors.
CASE PRESENTATION
We report on a case of ATRT in a 4-month-old infant conceived by in vitro fertilization (IVF). Some previous reports have raised a question about the possible relation between IVF and childhood cancer, particularly embryonal tumors.
CONCLUSION
Report of such cases may provide some evidence to identify if there is a real association between congenital tumors and IVF.
背景
非典型畸胎样/横纹肌样瘤（ATRT）是一种罕见的、极具侵袭性的中枢神经系统胚胎性肿瘤。婴儿期的脑肿瘤提示存在一些致癌的产前因素。
病例报告
我们报告一例通过体外受精（IVF）受孕的4个月大婴儿患ATRT的病例。此前一些报告对IVF与儿童癌症，尤其是胚胎性肿瘤之间的可能关系提出了疑问。
结论
此类病例报告可能为确定先天性肿瘤与IVF之间是否存在真正关联提供一些证据。
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