Cecen Emre, Gunes Dilek, Uysal Kamer Mutafoglu, Yuceer Nurullah, Ozer Erdener
Department of Pediatric Oncology, Adnan Menderes University School of Medicine, Aydin 09100, Turkey.
Childs Nerv Syst. 2010 Feb;26(2):263-6. doi: 10.1007/s00381-009-1005-5. Epub 2009 Nov 24.
Atypical teratoid/rhabdoid tumor (ATsRT) is a rare tumor and extremely aggressive embryonal neoplasm of the central nervous system. Brain tumors in infant are suggestive of some oncogenic prenatal factors.
We report on a case of ATRT in a 4-month-old infant conceived by in vitro fertilization (IVF). Some previous reports have raised a question about the possible relation between IVF and childhood cancer, particularly embryonal tumors.
Report of such cases may provide some evidence to identify if there is a real association between congenital tumors and IVF.
非典型畸胎样/横纹肌样瘤（ATRT）是一种罕见的、极具侵袭性的中枢神经系统胚胎性肿瘤。婴儿期的脑肿瘤提示存在一些致癌的产前因素。
我们报告一例通过体外受精（IVF）受孕的4个月大婴儿患ATRT的病例。此前一些报告对IVF与儿童癌症，尤其是胚胎性肿瘤之间的可能关系提出了疑问。
此类病例报告可能为确定先天性肿瘤与IVF之间是否存在真正关联提供一些证据。
