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足底压力评估对夏科氏关节病性中足畸形患者的预测价值。

Predictive values of foot plantar pressure assessment in patients with midfoot deformity secondary to Charcot neuroarthropathy.

机构信息

Diabetic Foot Unit, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.

Diabetic Foot Unit, Universidad Complutense de Madrid, Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (IdISSC), Madrid, Spain.

出版信息

Diabetes Res Clin Pract. 2021 May;175:108795. doi: 10.1016/j.diabres.2021.108795. Epub 2021 Apr 16.

DOI:10.1016/j.diabres.2021.108795
PMID:33872633
Abstract

AIMS

The principal aim of this study was to identify a cut-off point along the spectrum of peak plantar midfoot pressure that has an optimum combination of sensitivity and specificity to screen for neuropathic ulceration in patients with Charcot neuroarthropathy (CN).

METHODS

A 1-year outcome study was performed in twenty-five patients with diabetes, affected with chronic CN midfoot deformity. Peak plantar pressure (PPP) and pressure/time Integral (PTI) in the midfoot region were registered. For selecting the optimal diagnostic cut-off points on the scale of pressure measurement, ROC curves were used.

RESULTS

Twelve (48%) patients developed a plantar midfoot ulcer. Baseline PPP (24.04 ± 6.33 Vs. 12.85 ± 3.29 N/cm) and PTI (11.89 ± 4.60 Vs. 5.42 ± 2.26 N/cm/s) were significantly higher in the ulcerated group (p < .001 and p < .001, respectively). Using ROC analyses, optimal cut-off point for PPP was 16.45 N/cm, yielding a sensitivity of 92% and a specificity of 85%; and for PTI, optimal cut-off point was 7.2 N/cm/s, yielding a sensitivity of 92% and a specificity of 77%.

CONCLUSIONS

Patients with CN midfoot deformity with cut-off values for PPP of 16.45 N/cm and PTI of 7.2 N/cm/s showed an elevated risk of neuropathic ulceration in the plantar area of the midfoot.

摘要

目的

本研究的主要目的是确定沿足底中足峰值压力谱的一个切点,该切点具有最佳的敏感性和特异性组合,以筛查 Charcot 神经关节病(CN)患者的神经病变性溃疡。

方法

对 25 例糖尿病合并慢性 CN 中足畸形患者进行了为期 1 年的前瞻性研究。记录中足区域的峰值足底压力(PPP)和压力/时间积分(PTI)。为了在压力测量尺度上选择最佳的诊断截止点,使用 ROC 曲线。

结果

12 例(48%)患者发生足底中足溃疡。溃疡组的基线 PPP(24.04±6.33 对 12.85±3.29 N/cm)和 PTI(11.89±4.60 对 5.42±2.26 N/cm/s)显著升高(p<0.001 和 p<0.001)。ROC 分析显示,PPP 的最佳截断点为 16.45 N/cm,灵敏度为 92%,特异性为 85%;对于 PTI,最佳截断点为 7.2 N/cm/s,灵敏度为 92%,特异性为 77%。

结论

CN 中足畸形患者的 PPP 截断值为 16.45 N/cm,PTI 截断值为 7.2 N/cm/s,其足底中足区域发生神经病变性溃疡的风险增加。

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