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植物鞘脂类介绍及近期对其代谢与功能理解的进展综述。

An introduction to plant sphingolipids and a review of recent advances in understanding their metabolism and function.

作者信息

Lynch Daniel V, Dunn Teresa M

机构信息

Department of Biology, Williams College, Williamstown, MA 01267, USA.

Department of Biochemistry, Uniformed Services University of the Health Sciences, Bethesda, MD 20814, USA.

出版信息

New Phytol. 2004 Mar;161(3):677-702. doi: 10.1111/j.1469-8137.2004.00992.x. Epub 2004 Jan 14.

DOI:10.1111/j.1469-8137.2004.00992.x
PMID:33873728
Abstract

Sphingolipids are ubiquitous constituents of eukaryotic cells, and have been intensively investigated in mammals and yeast for decades. Aspects of sphingolipid biochemistry in plants have been explored only recently. To date, progress has been made in determining the structure and occurrence of sphingolipids in plant tissues; in characterizing the enzymatic steps involved in production and turnover of sphingolipids (and, in some cases, the genes encoding the relevant enzymes); and in identifying a variety of biological functions for sphingolipids in plants. Given that these efforts are far from complete and much remains to be learned, this review represents a status report on the burgeoning field of plant sphingolipid biochemistry. Contents Summary 677 I. Introduction 678 II. Plant sphingolipid structure 678 III. Sphingolipid metabolism in plants 683 IV. Sphingolipid functions in plants 693 V. Conclusions 696 Acknowledgements 696 References 696.

摘要

鞘脂是真核细胞中普遍存在的成分,几十年来在哺乳动物和酵母中得到了深入研究。植物鞘脂生物化学的各个方面直到最近才被探索。迄今为止,在确定植物组织中鞘脂的结构和存在情况、表征鞘脂产生和周转过程中涉及的酶促步骤(在某些情况下,还包括编码相关酶的基因)以及确定鞘脂在植物中的多种生物学功能方面都取得了进展。鉴于这些工作远未完成,仍有许多有待了解的地方,本综述代表了植物鞘脂生物化学这一新兴领域的现状报告。内容摘要677 一、引言678 二、植物鞘脂结构678 三、植物鞘脂代谢683 四、鞘脂在植物中的功能693 五、结论696 致谢696 参考文献696

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