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择期性与治疗性颈清扫术的比较发病率特征。

Comparative Morbidity Profile of Elective vs Therapeutic Neck Dissection.

机构信息

Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA.

出版信息

Otolaryngol Head Neck Surg. 2022 Feb;166(2):327-333. doi: 10.1177/01945998211008915. Epub 2021 Apr 20.

Abstract

OBJECTIVE

Neck dissection (ND) is one of the most commonly performed procedures in head and neck surgery. We sought to compare the morbidity of elective ND (END) versus therapeutic ND (TND).

STUDY DESIGN

Retrospective chart review.

SETTING

Academic tertiary care center.

METHODS

Retrospective chart review of 373 NDs performed from January 2015 to December 2018. Patients with radical ND or inadequate chart documentation were excluded. Demographics, clinicopathologic data, complications, and sacrificed structures during ND were retrieved. Statistical analysis was performed with χ and analysis of variance for comparison of categorical and continuous variables, respectively, with statistical alpha set a 0.05.

RESULTS

Patients examined consisted of 224 males (60%) with a mean age of 60 years. TND accounted for 79% (n = 296) as compared with 21% (n = 77) for END. Other than a significantly higher history of radiation (37% vs 7%, < .001) and endocrine pathology (34% vs 2.6%, < .001) in the TND group, no significant differences in demographics were found between the therapeutic and elective groups. A significantly higher rate of structure sacrifice and extranodal extension within the TND group was noted to hold in overall and subgroup comparisons. No significant difference in rate of surgical complications was appreciated between groups in overall or subgroup analysis.

CONCLUSION

While the significantly higher rate of structure sacrifice among the TND population represents an increased morbidity profile in these patients, no significant difference was found in the rate of surgical complications between groups. The significant difference seen between groups regarding history of radiation and endocrine pathology likely represents selection bias.

摘要

目的

颈清扫术(ND)是头颈部外科最常施行的手术之一。我们旨在比较择期颈清扫术(END)与治疗性颈清扫术(TND)的发病率。

研究设计

回顾性病历回顾。

设置

学术性三级护理中心。

方法

对 2015 年 1 月至 2018 年 12 月期间施行的 373 例 ND 进行回顾性病历回顾。排除根治性 ND 或病历记录不充分的患者。检索 ND 时的人口统计学、临床病理学数据、并发症以及牺牲的结构。采用 χ²检验和方差分析分别比较分类和连续变量,统计学α值设定为 0.05。

结果

检查的患者包括 224 例男性(60%),平均年龄为 60 岁。TND 占 79%(n = 296),而 END 占 21%(n = 77)。除 TND 组中显著更高的放疗史(37%比 7%, <.001)和内分泌病理学(34%比 2.6%, <.001)外,治疗组和择期组之间在人口统计学方面没有显著差异。在总体和亚组比较中,TND 组结构牺牲和淋巴结外扩展的发生率显著更高。在总体或亚组分析中,两组之间的手术并发症发生率没有显著差异。

结论

尽管 TND 人群中结构牺牲的发生率显著较高,代表这些患者的发病率更高,但两组之间的手术并发症发生率没有显著差异。在放疗史和内分泌病理学方面,两组之间的显著差异可能代表选择偏倚。

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