帕金森病患者/照护者配对中的应激-健康因素关联。
Association of Stress-Health Factors among Parkinson's Disease Patient/Caregiving-Partner Dyads.
出版信息
Arch Clin Neuropsychol. 2022 Jan 17;37(1):12-18. doi: 10.1093/arclin/acab024.
OBJECTIVE
Few studies have explored the shared effects of Parkinson's disease (PD) within patient/caregiver dyads. To fill this gap, we compared stress-health outcomes of patients with those of caregiving-partners, examined individual stress-health associations, and explored stress-health associations within dyads.
METHOD
A total of 18 PD patient/caregiving-partner dyads (N = 36) reported on disease-specific distress, anxiety, quality of life (QOL), and provided saliva samples for cortisol assessment. This cross-sectional, secondary analysis of a prospective pilot study used Actor-Partner Interdependence Models to test aims.
RESULTS
Patients reported greater anxiety, poorer QOL, and demonstrated flatter cortisol slopes and higher mean bedtime cortisol compared to caregiving-partners. Both patients and caregiving-partners with greater anxiety had elevated bedtime cortisol and poorer QOL. Greater disease-specific distress in an individual was associated with higher diurnal mean cortisol in their partner.
CONCLUSIONS
Findings highlight the potential for psychosocial interventions at the dyadic level to reduce shared burden and promote coping among PD patient/caregiving-partner dyads.
目的
鲜有研究探讨帕金森病（PD）患者/照料者二人组内的共同影响。为弥补这一空白，我们比较了患者和照料者的压力-健康结果，考察了个体压力-健康的关联，并探讨了二人组内的压力-健康关联。
方法
共纳入 18 对 PD 患者/照料者二人组（N=36），报告疾病特异性困扰、焦虑、生活质量（QOL），并提供唾液样本进行皮质醇评估。这是一项前瞻性初步研究的横断面、二次分析，采用演员-伙伴相互依存模型检验目的。
结果
与照料者相比，患者报告了更多的焦虑、较差的 QOL，并且表现出皮质醇斜率更平坦、睡前皮质醇更高。焦虑程度较高的患者和照料者均存在睡前皮质醇升高和 QOL 较差的情况。个体疾病特异性困扰越大，其伴侣的日间平均皮质醇越高。
结论
这些发现强调了在二人组层面实施心理社会干预的潜力，以减轻 PD 患者/照料者二人组的共同负担并促进应对。
Zotero 插件