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股骨骨折后残余内翻/外翻畸形愈合对膝关节生物力学影响的有限元分析。

Finite element analysis of biomechanical effects of residual varus/valgus malunion after femoral fracture on knee joint.

机构信息

Trauma Emergency Center, the Third Hospital of Hebei Medical University, No. 139 Ziqiang Road, Qiaoxi District, Shijiazhuang, 050051, People's Republic of China.

Key Laboratory of Biomechanics of Hebei Province, Orthopaedic Research Institute of Hebei Province, No.139 Ziqiang Road, Qiaoxi District, Shijiazhuang, 050051, Hebei, People's Republic of China.

出版信息

Int Orthop. 2021 Jul;45(7):1827-1835. doi: 10.1007/s00264-021-05039-9. Epub 2021 Apr 20.

Abstract

OBJECTIVE

Post-operative femoral shaft fractures are often accompanied by a residual varus/valgus deformity, which can result in osteoarthritis in severe cases. The purpose of this study was to investigate the biomechanical effects of residual varus/valgus deformities after middle and lower femoral fracture on the stress distribution and contact area of knee joint.

METHODS

Thin-slice CT scanning of lower extremities and MRI imaging of knee joints were obtained from a healthy adult male to establish normal lower limb model (neutral position). Then, the models of 3°, 5°, and 10° of varus/valgus were established respectively by modifying middle and lower femur of normal model. To validate the modifying, a patient-specific model, whose BMI was same to former and had 10° of varus deformity of tibia, was built and simulated under the same boundary conditions.

RESULT

The contact area and maximum stress of modified models were similar to those of patient-specific model. The contact area and maximum stress of medial tibial cartilage in normal neutral position were 244.36 mm and 0.64 MPa, while those of lateral were 196.25 mm and 0.76 MPa. From 10° of valgus neutral position to 10° of varus, the contact area and maximum stress of medial tibial cartilage increased, and the lateral gradually decreased. The contact area and maximum stress of medial meniscus in normal neutral position were 110.91 mm and 3.24 MPa, while those of lateral were 135.83 mm and 3.45 MPa. The maximum stress of medial tibia subchondral bone in normal neutral position was 1.47 MPa, while that of lateral was 0.65 MPa. The variation trend of medial/lateral meniscus and subchondral bone was consistent with that of tibial plateau cartilage in the contact area and maximum stress.

CONCLUSION

This study suggested that varus/valgus deformity of femur had an obvious effect on the contact area and stress distribution of knee joint, providing biomechanical evidence and deepening understanding when performing orthopedic trauma surgery or surgical correction of the already existing varus/valgus deformity.

摘要

目的

股骨中段和下段骨折术后常伴有残余内翻/外翻畸形,严重者可导致骨关节炎。本研究旨在探讨股骨中下段骨折后残余内翻/外翻畸形对膝关节应力分布和接触面积的生物力学影响。

方法

对 1 例健康成年男性下肢进行薄层 CT 扫描和膝关节 MRI 成像,建立正常下肢模型(中立位)。然后,通过修正正常模型的股骨中段和下段,分别建立 3°、5°和 10°内翻/外翻模型。为验证修正效果,建立了 1 例 BMI 与前者相同、胫骨有 10°内翻畸形的患者特定模型,并在相同边界条件下进行模拟。

结果

修正模型的接触面积和最大应力与患者特定模型相似。正常中立位时,内侧胫骨软骨的接触面积和最大应力分别为 244.36mm 和 0.64MPa,外侧分别为 196.25mm 和 0.76MPa。从 10°外翻中立位到 10°内翻,内侧胫骨软骨的接触面积和最大应力增加,外侧逐渐减小。正常中立位时,内侧半月板的接触面积和最大应力分别为 110.91mm 和 3.24MPa,外侧分别为 135.83mm 和 3.45MPa。正常中立位时,内侧胫骨软骨下骨的最大应力为 1.47MPa,外侧为 0.65MPa。内侧/外侧半月板和软骨下骨的最大应力变化趋势与胫骨平台软骨的接触面积和最大应力一致。

结论

本研究表明,股骨内翻/外翻畸形对膝关节的接触面积和应力分布有明显影响,为矫形创伤外科手术或已存在的内翻/外翻畸形的手术矫正提供了生物力学依据和深入认识。

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