Thorp B H, Duff S R
Institute for Grassland and Animal Production, Poultry Division, Roslin, Midlothian.
Res Vet Sci. 1988 Mar;44(2):164-74.
Fifteen broiler fowls which habitually adopted a unilateral weight bearing stance were studied. In the majority of fowls the left pelvic limb was weight bearing and the right limb showed severe angular deformity. Dyschondroplasia occurred most frequently in the load-bearing limb. In the load-bearing limb the majority of lesions were in the femur and proximal tibiotarsus. In the non-load-bearing limb lesions most frequently occurred in the bone extremities of the distal tibiotarsus and proximal tarsometatarsus. Occluded epiphyseal vascular canals occurred in conjunction with physeal thickening at some dyschondroplastic sites. The majority of dyschondroplastic lesions contained elongated penetrating epiphyseal vessels and vessels derived from the perichondrial ring. These vessels were associated with chondrocyte hypertrophy and matrix calcification, which was considered to lead to the repair of the lesions. There was minimal calcification of cartilage at the base of the dyschondroplastic lesions and the underlying metaphyseal vessels were blunt ending. This suggested that a band of abnormal physeal cartilage was acting as a barrier to penetration by the metaphyseal vessels and so preventing subsequent endochondral ossification.
对15只习惯性采取单侧负重姿势的肉鸡进行了研究。在大多数鸡中，左下肢承重，右下肢出现严重的角形畸形。软骨发育异常最常发生在承重肢体。在承重肢体中，大多数病变位于股骨和近端胫跗骨。在非承重肢体中，病变最常发生在远端胫跗骨和近端跗跖骨的骨端。在一些软骨发育异常的部位，骨骺血管管腔闭塞与骺板增厚同时出现。大多数软骨发育异常病变含有细长的穿透性骨骺血管和来自软骨膜环的血管。这些血管与软骨细胞肥大和基质钙化有关，被认为导致病变的修复。软骨发育异常病变底部的软骨钙化极少，其下方的干骺端血管呈钝端。这表明一条异常的骺板软骨带起到了阻挡干骺端血管穿透的屏障作用，从而阻止了随后的软骨内成骨。
