Deparment of Physics and Electronics, Osaka Prefecture University, Sakai, Osaka 599-8531, Japan.
JST PRESTO, Kawaguchi, Saitama 332-0012, Japan.
ACS Sens. 2021 May 28;6(5):1918-1924. doi: 10.1021/acssensors.1c00281. Epub 2021 Apr 20.
Continuous multiple data health monitoring has high potential to detect abnormal conditions or early stages of diseases in the future. To monitor a continuous small vital signal, one of the promising architectures is an attachable flexible multimodal sensor system, which can detect multiple health conditions from the skin surface. Recent breakthroughs have realized continuous sweat chemicals or physical conditions using flexible sensors. However, multimodal sensor integration to monitor chemical and physical information simultaneously and precisely is still a challenge. In this study, we present a multimodal wearable sensor sheet, which allows us to monitor sweat glucose, electrocardiograms, and skin temperature. Furthermore, to prevent the accumulation of glucose on the sensor surface for precise monitoring, a fluidic channel is also integrated to refresh the sweat from the sensor surface, resulting in the precise measurement of chemical substances in real time. This multimodal and flexible sensor platform takes a significant step toward realizing wearable healthcare applications to diagnose the early stages of diseases in advance.
连续的多数据健康监测具有很高的潜力，可以在未来检测到异常情况或疾病的早期阶段。为了监测连续的微小生命信号，一种很有前途的架构是可附着的灵活多模态传感器系统，它可以从皮肤表面检测多种健康状况。最近的突破已经实现了使用柔性传感器对连续汗液化学物质或物理条件的检测。然而，多模态传感器的集成仍然是一个挑战，以同时和精确地监测化学和物理信息。在这项研究中，我们提出了一种多模态可穿戴传感器片，可以监测汗液葡萄糖、心电图和皮肤温度。此外，为了防止葡萄糖在传感器表面积聚以进行精确监测，还集成了一个流体通道来从传感器表面更新汗液，从而实现实时精确测量化学物质。这种多模态和灵活的传感器平台朝着实现可穿戴医疗应用以提前诊断疾病早期阶段迈出了重要一步。
