Mitochondria-Targeted Red-Emission Fluorescent Probe for Ultrafast Detection of HS in Food and Its Bioimaging Application.

Hydrogen sulfide (HS) contributes to human health and prolongs the storage time of postharvest fruits and vegetables. At the same time, HS can cause a negative impact on some foodstuffs and beverages, so an efficient probe to detect HS is needed. Herein, a fluorescent turn-on responding probe for HS detection has been designed and synthesized. exhibited a red emission (608 nm), large Stokes shift (111 nm), and a detection limit of a nanomolar level (356 nM) in a dimethylformamide/phosphate-buffered saline (DMF/PBS) (1:1, v/v, 10 mM, pH 7.4) solution. can detect HS with ultrafast response within 4 s, which is faster than the response of other reported probes. In addition, the applicability of to detect HS has been determined in the actual water samples, targeted mitochondria, and imaged HS in living cells. Moreover, was successfully used as a tool to judge HS levels in beer, which indicates that possesses the advantage of rapid detection of HS in foodstuffs.