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瑞典面包师和糕点厨师的肺癌发病率:时间变化

Lung cancer incidence among Swedish bakers and pastrycooks: temporal variation.

作者信息

Carstensen J M, Wicksell L, Eklund G, Gustafsson J A

机构信息

Department of Cancer Epidemiology, Radiumhemmet, Karolinska University Hospital, Stockholm, Sweden.

出版信息

Scand J Soc Med. 1988;16(2):81-5. doi: 10.1177/140349488801600204.

Abstract

In a cohort of Swedish bakers and pastrycooks, based on the census of 1960, 188 male lung cancer cases, were reported to the national Cancer Registry 1961-79. The risk of lung cancer exceeded that of all men with 43% (confidence interval 23-65%). After adjustment for smoking habits, using data from a sample of one percent of the Swedish population, the excess risk was reduced. There was a temporal variation in the relative risk, which decreased during the follow-up period in the younger birth cohorts but not in the older ones. Changes in smoking habits did not seem to explain the decreasing trend. The lung cancer risk did not differ significantly between employees and those self-employed in the cohort. To some extent these results confirm earlier findings concerning excess risks of lung cancer in bakers. The lowered risk in Sweden towards the end of the seventies, suggests that the problem is now of less importance.

摘要

在一组瑞典面包师和糕点师中,根据1960年的人口普查,188例男性肺癌病例在1961年至1979年期间被报告给国家癌症登记处。肺癌风险比所有男性高出43%(置信区间为23%至65%)。根据瑞典1%人口样本的数据对吸烟习惯进行调整后,超额风险有所降低。相对风险存在时间变化,在随访期间,较年轻出生队列的相对风险下降,而较年长队列则没有。吸烟习惯的变化似乎无法解释这种下降趋势。该队列中雇员和自营职业者的肺癌风险没有显著差异。这些结果在一定程度上证实了早期关于面包师肺癌超额风险的研究发现。瑞典在70年代末风险降低,表明这个问题现在的重要性有所降低。

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