两种病毒的故事：细小病毒B19和艾滋病毒。
Tale of two viruses: parvovirus B19 and HIV.
作者信息
Hernstadt Hayley, Randell Paul, Fidler Sarah, Foster Caroline
机构信息
Department of Paediatric Infectious Diseases, Imperial College Healthcare NHS Trust, London, UK
Department of Paediatrics, Monash University, Melbourne, VIC, Australia.
出版信息
BMJ Case Rep. 2021 Apr 20;14(4):e239153. doi: 10.1136/bcr-2020-239153.
We present a HIV-infected patient who developed severe anaemia due to chronic parvovirus B19 infection and subsequently had an unplanned pregnancy. This is in the context of poor adherence to antiretroviral therapy and significant immunosuppression; there was a delay in diagnosis of chronic parvovirus infection due to attribution of anaemia to HIV. She received immunoglobulin therapy and effective antiretroviral therapy, with reduction in parvovirus load and improvement in anaemia. She was counselled regarding the need for monitoring in pregnancy due to risk of intrauterine infection. We review the literature of management of chronic parvovirus infection in the immunosuppressed and the consequences of intrauterine infection.
我们报告了一名感染人类免疫缺陷病毒（HIV）的患者，该患者因慢性细小病毒B19感染而出现严重贫血，随后意外怀孕。这发生在对抗逆转录病毒疗法依从性差且存在显著免疫抑制的背景下；由于将贫血归因于HIV，慢性细小病毒感染的诊断出现延迟。她接受了免疫球蛋白治疗和有效的抗逆转录病毒治疗，细小病毒载量降低，贫血情况改善。鉴于存在宫内感染风险，我们为她提供了孕期监测必要性的咨询。我们回顾了免疫抑制患者慢性细小病毒感染的管理文献以及宫内感染的后果。
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