Gor Dhairya, Singh Vinit, Gupta Varsha, Levitt Michael
Internal Medicine, Jersey Shore University Medical Center, Neptune, USA.
Internal Medicine, Monmouth Medical Center, Long Branch, USA.
Cureus. 2022 Apr 30;14(4):e24627. doi: 10.7759/cureus.24627. eCollection 2022 Apr.
Anemia is a common finding in a human immunodeficiency virus (HIV)-positive patient with a wide range of possible causes and is a significant risk factor for mortality in acquired immunodeficiency syndrome (AIDS). Opportunistic parvovirus infection-causing pure red cell aplasia is one of its uncommon causes. It has been suggested that immunocompromised patients with abnormal antibody production are more susceptible to acquiring a chronic parvovirus infection requiring long-term intravenous immunoglobulin (IVIg) treatment; however, there are no specific guidelines for it. Here, we present a case of an HIV patient with persistent parvovirus infection resulting in chronic anemia requiring long-term maintenance immunoglobulin therapy with an excellent therapeutic response.
贫血是人类免疫缺陷病毒（HIV）阳性患者的常见表现，其病因众多，也是获得性免疫缺陷综合征（AIDS）患者死亡的重要危险因素。由机会性细小病毒感染引起的纯红细胞再生障碍是其少见病因之一。有研究表明，抗体产生异常的免疫功能低下患者更容易感染慢性细小病毒，需要长期静脉注射免疫球蛋白（IVIg）治疗；然而，目前尚无针对此的具体指南。在此，我们报告一例HIV患者，其持续性细小病毒感染导致慢性贫血，需要长期维持免疫球蛋白治疗，且治疗反应良好。
