Jiangxi University of Traditional Chinese Medicine.
Science and Technology College of Jiangxi University of Traditional Chinese Medicine, Nanchang, China.
Medicine (Baltimore). 2021 Apr 23;100(16):e25562. doi: 10.1097/MD.0000000000025562.
Peptic ulcer (PU) is a common clinical disease of the digestive system, which can occur in all ages, gastric and duodenal ulcers are the most commonly seen PUs in clinical practice. The main manifestations are chronic and periodic rhythmic upper abdominal pain, accompanied by indigestion symptoms such as pantothenic acid, belching, and nausea. Serious complications such as bleeding, perforation, obstruction and canceration are easy to occur, endangering the life safety of patients. There are many ways to treat PU in clinic, and acupoint catgut embedding therapy has its unique advantages. Hence, our systematic review aims to evaluate the efficacy and safety of acupoint embedding therapy in the treatment of PU and to provide a reliable basis for physician.
We will search electronic databases including PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database (WF), China Biomedical Literature Database (CBM), and China Scientific Journals Database (VIP) from establishment to April 2021, and will manually searched the list of medical journals as a supplement. Two authors will screen the studies independently, as well as extract data information, and assess methodological quality through the Cochrane risk of bias (ROB) tool. The Stata software (Version 16.0) software will be used for statistical analysis.
By evaluating the current status of acupoint catgut embedding for Peptic ulcer disease, this study would prove the effectiveness and safety of acupoint embedding therapy, and will be published in a peer-reviewed journal.
This systematic review will provide a credible evidence-based for acupoint catgut embedding in the treatment of peptic ulcer.
INPLASY202130097.
消化性溃疡（PU）是一种常见的消化系统疾病，可发生于各年龄段，其中以胃溃疡和十二指肠溃疡最为常见。主要表现为慢性、周期性、节律性上腹痛，伴有反酸、嗳气等消化不良症状。易发生出血、穿孔、梗阻和癌变等严重并发症，危及患者生命安全。临床上治疗 PU 的方法很多，穴位埋线疗法具有独特的优势。因此，本系统评价旨在评估穴位埋线疗法治疗 PU 的疗效和安全性，为临床医生提供可靠的依据。
我们将检索包括 PubMed、Embase、Cochrane 图书馆、中国知网（CNKI）、万方数据库（WF）、中国生物医学文献数据库（CBM）和中国科技期刊数据库（VIP）在内的电子数据库，从建库到 2021 年 4 月，并将作为补充手动搜索医学期刊列表。两名作者将独立筛选研究，以及提取数据信息，并通过 Cochrane 偏倚风险（ROB）工具评估方法学质量。使用 Stata 软件（版本 16.0）进行统计分析。
通过评估穴位埋线治疗消化性溃疡的现状，本研究将证明穴位埋线疗法的有效性和安全性，并将发表在同行评议的期刊上。
本系统评价将为穴位埋线治疗消化性溃疡提供可靠的循证医学证据。
INPLASY 注册号：INPLASY202130097.
