School of Acupuncture-Moxibustion and Tuina.
School of Nursing.
Medicine (Baltimore). 2021 Jan 29;100(4):e24286. doi: 10.1097/MD.0000000000024286.
This review will assess current evidence related to the effectiveness and safety of acupoint catgut embedding therapy for functional constipation (FC) and provide efficacy assessments for clinical applications.
We will search the following databases for relevant trials: PubMed, EMBASE OVID, Cumulative Index of Nursing and Allied Health Literature, OVID MEDLINE, Web of Science, the Cochrane Central Register of Controlled Trials, Cochrane library, and Scopus. We will also search the following Chinese databases for trials published in the Chinese literature: China National Knowledge Infrastructure Database (CNKI), Chinese Scientific Journals Database, Wan Fang Database, Chinese Biomedicine and other resources from inception to December 2020. Only randomized controlled trials comparing acupoint catgut embedding versus acupuncture or sham acupuncture or placebo or other therapies will be included. The outcomes involved mean spontaneous bowel movements, complete spontaneous bowel movements, the Bristol Stool Form Scale, the Cleveland Clinic Score, Patient Assessment of Constipation symptom and so on. The risk of bias assessment and quality of evidence for outcomes will be appraised using the Cochrane Risk of Bias Tool and the Grading of Recommendations, Assessment, Development and Evaluation guidelines. RevMan 5.3 software will be employed for the meta-analysis.
This work will compare and arrange the comparative efficacy of acupoint catgut embedding with different treatments for FC by summarizing the current evidences.
The results of this meta-analysis may help doctors determine the best treatments for patients to manage FC.
This is a protocol with no patient recruitment and personal information collection, approval by the ethics committee is not required.
DOI 10.17605/OSF.IO/XTKE2.
本综述旨在评估穴位埋线疗法治疗功能性便秘（FC）的有效性和安全性的现有证据，并为临床应用提供疗效评估。
我们将检索以下数据库中的相关试验：PubMed、EMBASE OVID、护理学及相关健康学科累积索引、OVID MEDLINE、Web of Science、Cochrane 对照试验中心注册库、Cochrane 图书馆和 Scopus。我们还将检索中国文献中的以下中文数据库中的试验：中国国家知识基础设施数据库（CNKI）、中国科学期刊数据库、万方数据库、中国生物医学文献数据库等，检索时间截至 2020 年 12 月。仅纳入比较穴位埋线与针灸或假针灸或安慰剂或其他疗法的随机对照试验。结局指标包括自发排便次数、完全自发排便次数、布里斯托大便形状量表、克利夫兰诊所评分、患者便秘症状评估等。采用 Cochrane 偏倚风险工具和推荐评估、制定与评价指南对结局的偏倚风险评估和证据质量进行评价。使用 RevMan 5.3 软件进行荟萃分析。
本研究将通过总结现有证据，比较和整理穴位埋线与不同治疗方法治疗 FC 的比较疗效。
荟萃分析的结果可能有助于医生确定治疗 FC 的最佳方法。
本研究是一份方案，不涉及患者招募和个人信息收集，不需要伦理委员会的批准。
OSF 注册号：DOI 10.17605/OSF.IO/XTKE2。
