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探索课堂中的神经可塑性:通过一项中风患者研究讲授视觉系统中的皮质重组

Exploring Neuroplasticity in the Classroom: Teaching Cortical Reorganization in the Visual System with a Stroke Patient Study.

作者信息

Housman Hope A R

机构信息

School of Psychology and Neuroscience, University of St. Andrews, St. Andrews, Scotland, United Kingdom KY16 9JP.

出版信息

J Undergrad Neurosci Educ. 2020 Dec 31;19(1):R15-R18. eCollection 2020 Fall.

Abstract

Neuroscience education often dedicates a substantial amount of time to the study of neuroplasticity and cortical reorganization. Research articles that demonstrate neuroplasticity and cortical reorganization in human patients provide opportunities for neuroscience education. Dilks et al., in a 2007 article published in the provided evidence for cortical reorganization within the human primary visual cortex by utilizing both behavioral and fMRI data. The study examined stroke patient B.L. who was cortically blind in the upper left visual field. In the presence of visual stimuli from the lower left visual field, cortical reorganization allowed for the activation of areas of V1 that would not normally respond to this visual information. Therefore, B.L. perceived visual stimuli presented in the lower left visual field to be vertically elongated into the upper left visual field (Dilks et al., 2007). This paper is an ideal platform for teaching an undergraduate neuroscience audience about neuroplasticity within the human brain. The article allows students to combine knowledge of both the visual system and neuroplasticity and provides a visual representation of cortical reorganization that helps facilitate understanding of principles of neuroscience.

摘要

神经科学教育通常会投入大量时间来研究神经可塑性和皮质重组。展示人类患者神经可塑性和皮质重组的研究文章为神经科学教育提供了契机。迪克斯等人在2007年发表于《 》的一篇文章中,通过运用行为学和功能磁共振成像(fMRI)数据,为人类初级视觉皮质内的皮质重组提供了证据。该研究考察了中风患者B.L.,其左上视野皮质盲。在来自左下视野的视觉刺激存在的情况下,皮质重组使得通常不会对该视觉信息做出反应的V1区域被激活。因此,B.L.将呈现于左下视野的视觉刺激感知为垂直延伸到了左上视野(迪克斯等人,2007年)。这篇论文是向本科神经科学受众传授人类大脑神经可塑性的理想平台。该文章让学生能够将视觉系统知识与神经可塑性知识相结合,并提供了皮质重组的视觉呈现,有助于促进对神经科学原理的理解。

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