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原发性胸骨结核性骨髓炎:慢性胸痛的罕见病因。

Primary Sternal Tubercular Osteomyelitis: A Rare Cause of Chronic Chest Pain.

作者信息

Saif Hani

机构信息

Obstetrics and Gynecology, Niger Central Hospital, Niamey, NER.

出版信息

Cureus. 2021 Mar 17;13(3):e13959. doi: 10.7759/cureus.13959.

DOI:10.7759/cureus.13959
PMID:33880294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8052211/
Abstract

Sternal osteomyelitis is a rare clinical condition that occasionally develops when there is an adjacent focus of infection. However, primary sternal tubercular osteomyelitis is an extremely rare form. We describe the case of a 52-year-old Indian male who presented with a two-year history of central chest pain. The pain was not related to exercise, meals, or respiration. There was no history of cough, fever, or weight loss. On examination, there was tenderness over the sternum and the patient was diagnosed as having costochondritis. However, the patient's condition did not improve and he developed erythematous skin changes over the sternum. A computed tomography scan of the chest demonstrated destructive sternal lesions. Subsequently, a biopsy was taken which revealed the diagnosis of tuberculosis. The patient was managed by anti-tubercular therapy and had complete resolution of symptoms. Clinicians should keep this condition in the differential diagnosis of chronic chest pain mimicking the diagnosis of costochondritis, particularly in patients from endemic areas.

摘要

胸骨骨髓炎是一种罕见的临床病症,在存在相邻感染灶时偶尔会发生。然而,原发性胸骨结核性骨髓炎是一种极为罕见的形式。我们描述了一名52岁印度男性的病例,该患者有两年的胸痛病史。疼痛与运动、饮食或呼吸无关。无咳嗽、发热或体重减轻史。检查时,胸骨有压痛,患者被诊断为肋软骨炎。然而,患者的病情并未改善,胸骨处出现了皮肤红斑变化。胸部计算机断层扫描显示胸骨有破坏性病变。随后进行了活检,结果显示为结核病。患者接受了抗结核治疗,症状完全缓解。临床医生在鉴别诊断类似肋软骨炎的慢性胸痛时,应考虑到这种病症,特别是在来自流行地区的患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1804/8052211/631f1e81d763/cureus-0013-00000013959-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1804/8052211/631f1e81d763/cureus-0013-00000013959-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1804/8052211/631f1e81d763/cureus-0013-00000013959-i01.jpg

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本文引用的文献

1
Primary Sternal Osteomyelitis: A Case Report and Review.原发性胸骨骨髓炎:一例报告及文献复习
Plast Reconstr Surg Glob Open. 2019 Jun 12;7(6):e2120. doi: 10.1097/GOX.0000000000002120. eCollection 2019 Jun.
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Primary sternal tuberculosis mimicking a lytic bone tumor lesion.酷似溶骨性骨肿瘤病变的原发性胸骨结核
Monaldi Arch Chest Dis. 2018 May 28;88(1):931. doi: 10.4081/monaldi.2018.931.
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Primary sternal tuberculosis osteomyelitis: A case report and discussion.原发性胸骨骨髓炎:一例病例报告并讨论。
Can J Infect Dis Med Microbiol. 2009 Winter;20(4):e181-4. doi: 10.1155/2009/484712.
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Tuberculosis of the sternum: a clinical study.胸骨结核:一项临床研究。
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