Chehrastane Ghizlane, Benaissa Elmostafa, Radi Abdelilah, El Hassani Amal, Elouennass Mostafa
Department of Microbiology, Mohammed V Military Instruction Hospital, Rabat, Morocco.
Department of Pediatrics and Neonatology, Mohammed V Military Instruction Hospital, Rabat, Morocco.
Access Microbiol. 2024 Aug 5;6(8). doi: 10.1099/acmi.0.000795.v3. eCollection 2024.
Tuberculosis (TB) is one of the most common pathogens of bacterial lung infections, especially in underdeveloped nations like Morocco, where the incidence of TB was 97 cases per 100 000 persons in 2019. Thanks to its national TB prevention and control plan, Morocco was able to achieve remarkable progress in the management of TB with an 80% reduction in the total number of patients diagnosed with TB between 1980 and 2018. The national plan also allowed us to reach and maintain a therapeutic rate above 86% since 2002. Sternal TB is a rare clinical condition accounting for 1% of all musculoskeletal TB cases. Due to its rarity and the lack of awareness of clinical presentations, the diagnosis of sternal TB can be quite complex. We describe the case of a 14-year-old Moroccan patient consulting in the Military Hospital Mohammed V-Rabat with central chest pain for 4 months which was not associated with breathing, physical exercise or eating. The patient also had a history of asthenia, fever and weight loss. A computed tomography scan of the chest showed a destructive lesion of the sternum. Afterward, a chirurgical biopsy was performed and enabled to confirm the microbiological diagnosis of TB with the realization of the real-time PCR. The antitubercular therapy was given to the patient who had complete resolution of symptoms. This condition should be included in the differential diagnosis of chronic chest pain that mimics costochondritis particularly in patients from endemic areas.
结核病(TB)是细菌性肺部感染最常见的病原体之一,尤其是在摩洛哥等不发达国家,2019年该国的结核病发病率为每10万人中有97例。得益于其国家结核病预防和控制计划,摩洛哥在结核病管理方面取得了显著进展,1980年至2018年间确诊的结核病患者总数减少了80%。自2002年以来,该国家计划还使我们能够达到并维持86%以上的治疗率。胸骨结核是一种罕见的临床病症,占所有肌肉骨骼结核病病例的1%。由于其罕见性以及对临床表现缺乏认识,胸骨结核的诊断可能相当复杂。我们描述了一名14岁摩洛哥患者的病例,该患者在拉巴特穆罕默德五世军事医院就诊,主诉胸部中央疼痛4个月,与呼吸、体育锻炼或进食无关。患者还伴有乏力、发热和体重减轻史。胸部计算机断层扫描显示胸骨有破坏性病变。随后进行了手术活检,并通过实时聚合酶链反应确诊为结核病。给予该患者抗结核治疗后,症状完全缓解。这种病症应纳入慢性胸痛的鉴别诊断,尤其是在来自流行地区的患者中,慢性胸痛可能会误诊为肋软骨炎。