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从软组织和硬组织(膝关节)、有限元分析和 3D 打印进行高生物逼真度 3D 生物模型重建:一种三维方法学提案。

High Biofidelity 3D Biomodel Reconstruction from Soft and Hard Tissues (Knee), FEM, and 3D Printing: A Three-Dimensional Methodological Proposal.

机构信息

Instituto Politécnico Nacional, Escuela Superior de Ingeniería Mecánica y Eléctrica, Sección de Estudios de Posgrado e Investigación, Unidad Profesional Adolfo López Mateos "Zacatenco", Avenida Instituto Politécnico Nacional s/n, Edificio 5, 2do. Piso, Col, Lindavista, C.P. 07320 Ciudad de, Mexico.

Universidad Politécnica del Valle de México, Departamento de Mecatrónica, Av. Mexiquense s/n esquina Av. Universidad Politécnica, Col. Villa Esmeralda, Tultitlán, C.P. 54910 Estado de, Mexico.

出版信息

Biomed Res Int. 2021 Apr 3;2021:6688164. doi: 10.1155/2021/6688164. eCollection 2021.

Abstract

The modelling of biological structures has allowed great advances in Engineering, Biology, and Medicine. In turn, these advances are seen from the design of footwear and sports accessories, to the design of prostheses, accessories and rehabilitation treatments. The reproduction of the various tissues has gone through an important evolution thanks to the development of computer systems and programs. However, knowledge of the medical-biological and engineering areas continues to be required, and it involves a considerable investment of time and resources. The resulting biomodels still require great precision. The present work shows a methodology that allows to optimize computational resources and reduce elaboration time of biomodels. Through this methodology, it is possible to generate a biomodel of high biofidelity of a human knee. This biomodel is constituted by hard tissues (cortical and trabecular bones) and soft tissues (ligaments and meniscus) resulting in the modelling of the lower third of the femur, the tibial plateaus, the anterior cruciate ligament, posterior cruciate ligament, external lateral ligament, interior lateral ligaments, and the meniscus. With this model and methodology, it is possible to perform numerical analyses that will provide results very similar to those of real life. As, the methodology allows to assign the mechanical properties to each tissue and the anatomical structure.

摘要

生物结构建模使得工程学、生物学和医学取得了重大进展。反过来,这些进展体现在从鞋类和运动配件的设计,到假肢、配件和康复治疗的设计。由于计算机系统和程序的发展,各种组织的复制经历了重要的演变。然而,仍然需要医学-生物学和工程领域的知识,这涉及到相当大的时间和资源投入。由此产生的生物模型仍然需要很高的精度。本工作展示了一种方法,该方法允许优化计算资源并减少生物模型的制作时间。通过这种方法,可以生成一个具有高度生物逼真度的人类膝关节生物模型。该生物模型由硬组织(皮质骨和松质骨)和软组织(韧带和半月板)组成,从而对股骨的下三分之一、胫骨平台、前交叉韧带、后交叉韧带、外侧外侧韧带、内侧内侧韧带和半月板进行建模。使用该模型和方法,可以进行数值分析,提供非常接近实际情况的结果。因为,该方法允许为每个组织和解剖结构分配机械性能。

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