Primary resistance to CD19-directed chimeric antigen receptor T-cell therapy in T-cell/histiocyte-rich large B-cell lymphoma.
作者信息
Trujillo Jonathan A, Godfrey James, Hu Yifei, Huang Jun, Smith Sonali M, Frigault Matthew J, DeFilipp Zachariah, Appelbaum Daniel, Pu Yonglin, Feinberg Nicholas, Althaus Thomas, Bishop Michael R, Riedell Peter A, Kline Justin
机构信息
Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.
Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.
出版信息
Blood. 2021 Jun 17;137(24):3454-3459. doi: 10.1182/blood.2020009148.
Abstract
摘要
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Blood. 2021 Mar 11;137(10):1353-1364. doi: 10.1182/blood.2020006464.
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High metabolic tumor volume is associated with decreased efficacy of axicabtagene ciloleucel in large B-cell lymphoma.高代谢肿瘤体积与 axicabtagene ciloleucel 在大 B 细胞淋巴瘤中的疗效降低有关。
Blood Adv. 2020 Jul 28;4(14):3268-3276. doi: 10.1182/bloodadvances.2020001900.
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The immune landscape and response to immune checkpoint blockade therapy in lymphoma.淋巴瘤的免疫景观与免疫检查点阻断治疗反应。
Blood. 2020 Feb 20;135(8):523-533. doi: 10.1182/blood.2019000847.
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Clinical features and survival of patients with T-cell/histiocyte-rich large B-cell lymphoma: analysis of the National Cancer Data Base.T 细胞/组织细胞丰富型大 B 细胞淋巴瘤患者的临床特征和生存分析：国家癌症数据库分析。
Leuk Lymphoma. 2019 Dec;60(14):3426-3433. doi: 10.1080/10428194.2019.1639166. Epub 2019 Jul 9.
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gene alterations identify a subset of diffuse large B-cell lymphoma harboring a T-cell-inflamed phenotype.基因改变鉴定出具有 T 细胞炎症表型的弥漫性大 B 细胞淋巴瘤亚群。
Blood. 2019 May 23;133(21):2279-2290. doi: 10.1182/blood-2018-10-879015. Epub 2019 Mar 25.
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ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells.ASTCT 细胞因子释放综合征和免疫效应细胞相关神经系统毒性的共识分级标准。
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Long-term safety and activity of axicabtagene ciloleucel in refractory large B-cell lymphoma (ZUMA-1): a single-arm, multicentre, phase 1-2 trial.阿基仑赛注射液治疗难治性大 B 细胞淋巴瘤的长期安全性和疗效（ZUMA-1）：一项单臂、多中心、1-2 期临床试验。
Lancet Oncol. 2019 Jan;20(1):31-42. doi: 10.1016/S1470-2045(18)30864-7. Epub 2018 Dec 2.
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N Engl J Med. 2019 Jan 3;380(1):45-56. doi: 10.1056/NEJMoa1804980. Epub 2018 Dec 1.
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, , , and are frequently mutated in T-cell/histiocyte-rich large B-cell lymphoma.在 T 细胞/组织细胞丰富性大 B 细胞淋巴瘤中，经常发生 、 、 和 的突变。
Haematologica. 2019 Feb;104(2):330-337. doi: 10.3324/haematol.2018.203224. Epub 2018 Sep 13.
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T-cell/histiocyte-rich large B-cell lymphoma.富于T细胞/组织细胞的大B细胞淋巴瘤
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