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Primary resistance to CD19-directed chimeric antigen receptor T-cell therapy in T-cell/histiocyte-rich large B-cell lymphoma.

作者信息

Trujillo Jonathan A, Godfrey James, Hu Yifei, Huang Jun, Smith Sonali M, Frigault Matthew J, DeFilipp Zachariah, Appelbaum Daniel, Pu Yonglin, Feinberg Nicholas, Althaus Thomas, Bishop Michael R, Riedell Peter A, Kline Justin

机构信息

Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL.

Department of Hematology and Hematopoietic Cell Transplantation, City of Hope, Duarte, CA.

出版信息

Blood. 2021 Jun 17;137(24):3454-3459. doi: 10.1182/blood.2020009148.

Abstract
摘要

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gene alterations identify a subset of diffuse large B-cell lymphoma harboring a T-cell-inflamed phenotype.
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, , , and are frequently mutated in T-cell/histiocyte-rich large B-cell lymphoma.
Haematologica. 2019 Feb;104(2):330-337. doi: 10.3324/haematol.2018.203224. Epub 2018 Sep 13.
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T-cell/histiocyte-rich large B-cell lymphoma.
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