Murayama M
Laboratory of Physical Biology, NIAMS, Bethesda, Maryland 20892.
Thromb Res. 1988 Mar 15;49(6):539-48. doi: 10.1016/0049-3848(88)90251-4.
We report here that the rate of fibrin polymerization is accelerated by decompression: the rate is essentially doubled by reducing the pressure by one-half (380 torr, 14.7 PSI or 1/2 ATM) and increased by 3.6 times with respect to the control at 25 torr (0.48 PSI or 1/30th ATM). We also report here that the rate of fibrin polymerization is decelerated by compression; at 5.2 X 10(5) torr (10,000 PSI or 680 ATM) polymerization is inhibited and/or reversed.
我们在此报告,减压可加速纤维蛋白聚合速率:压力减半(380托,14.7磅力/平方英寸或1/2标准大气压)时,速率基本翻倍;在25托(0.48磅力/平方英寸或1/30标准大气压)下,相对于对照,速率增加3.6倍。我们还在此报告,压缩会使纤维蛋白聚合速率减慢;在5.2×10⁵托(10,000磅力/平方英寸或680标准大气压)时,聚合受到抑制和/或逆转。