Oosterbaan H P, Swaab D F
Groot Ziekengasthuis, Afd. Gynaecologie en Verloskunde, 's-Hertogenbosch.
Tijdschr Diergeneeskd. 1988 Jun 15;113(12):677-80.
Oxytocin and vasopressin are hormones having a number of peripheral and (more recently detected) central activities. The two peptides are found to be present in both human amniotic fluid and in that of rats. The origin of these substances was studied in combined clinical and experimental investigations, as were also the relationships of these compounds with intra-uterine growth and the process of labour. Oxytocin was not found to originate from the foetal brain, the foetal adrenals being suggested as a possible alternative source. There was found to be a positive correlation between amniotic oxytocin and measures of the foetal brain, amniotic vasopressin possibly reflecting a poor condition of the foetus (stress?).
催产素和加压素是具有多种外周及(最近发现的)中枢活性的激素。人们发现这两种肽存在于人类羊水和大鼠羊水中。在临床与实验相结合的研究中,对这些物质的来源以及这些化合物与子宫内生长和分娩过程的关系进行了研究。未发现催产素源自胎儿大脑,有人提出胎儿肾上腺可能是另一种可能的来源。发现羊水催产素与胎儿大脑指标之间存在正相关,羊水加压素可能反映胎儿状况不佳(应激?)。