Pediatric Neurosurgery Department, Dr. Asenjo Neurosurgical Institute, Santiago, Chile.
Radioneurosurgery and Functional Neurosurgery Unit, Sheba Medical Center, Ramat Gan, Israel.
Childs Nerv Syst. 2021 Dec;37(12):3923-3932. doi: 10.1007/s00381-021-05173-0. Epub 2021 Apr 22.
Primary intracranial smooth muscle tumors are rare. Most cases are related to Epstein-Barr virus proliferation in immunocompromised patients such as organ solid recipients. Only a few cases have been reported in pediatric patients. The clinical features are very variable depending mainly on the location and size of the smooth muscle tumor (SMT) and the pathogenesis is poorly understood. We describe two cases of intracranial SMT localized in the temporal lobe and associated with EBV in immunosuppressed children. A review of the literature associated with intracranial leiomyomas was also done.
原发性颅内平滑肌肉瘤较为罕见。大多数病例与免疫功能低下患者（如实体器官受者）中的 EBV 增殖有关。在儿科患者中，仅有少数病例报道。临床表现变化多样，主要取决于平滑肌肿瘤（SMT）的位置和大小，发病机制尚不清楚。我们描述了 2 例位于颞叶且与 EBV 相关的颅内 SMT 发生于免疫抑制儿童。同时还对与颅内平滑肌瘤相关的文献进行了回顾。
