艾滋病患者继发于高级别 B 细胞胃淋巴瘤的胃结肠瘘：一例报告。

A gastro-colic fistula secondary to high-grade B-cell gastric lymphoma in a patient with AIDS: a case report.

机构信息

Division of Gastroenterology & Hepatology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.

Department of Accident & Emergency, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China.

出版信息

J Int Med Res. 2021 Apr;49(4):3000605211006602. doi: 10.1177/03000605211006602.

DOI:10.1177/03000605211006602

PMID:33884916

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8074477/

Abstract

To the best of our knowledge, there are no previous reports of a gastro-colic fistula (GCF) secondary to primary high-grade B-cell gastric lymphoma associated with acquired immunodeficiency syndrome (AIDS). Here, we report a 37-year-old man who presented with paroxysmal abdominal pain for 4 months, diarrhea for 15 days and weight loss of 4 kg. He had a history of human immunodeficiency virus (HIV) infection and was diagnosed with AIDS in 2013. The patient was diagnosed with a GCF secondary to primary high-grade B-cell gastric lymphoma by gastroscopy and histopathological examination. Two weeks after diagnosis, he died in another hospital. This is an uncommon case in which the GCF occurred secondary to malignant gastric lymphoma in a patient with AIDS. Supported by the literature, patients with HIV infection who complain of abdominal pain or a mass, severe diarrhea, and weight loss should be assessed for a GCF secondary to lymphoma because of its worse prognosis.

摘要

据我们所知，目前尚无原发性高级别 B 细胞胃淋巴瘤合并获得性免疫缺陷综合征（AIDS）继发胃肠瘘（GCF）的报道。在此，我们报告了 1 例 37 岁男性患者，其主要表现为阵发性腹痛 4 个月，腹泻 15 天，体重减轻 4kg。该患者有人类免疫缺陷病毒（HIV）感染史，并于 2013 年被诊断为 AIDS。该患者通过胃镜和组织病理学检查诊断为原发性高级别 B 细胞胃淋巴瘤继发 GCF。诊断后 2 周，他在另一家医院死亡。这是一例罕见病例，AIDS 患者恶性胃淋巴瘤继发 GCF。根据文献，HIV 感染患者出现腹痛或肿块、严重腹泻和体重减轻时，应评估是否存在继发于淋巴瘤的 GCF，因为其预后更差。