Division of Nephrology, Department of Internal Medicine, Showa University Fujigaoka Hospital, Yokohama, Japan.
Showa University Research Administration Center (SURAC), Showa University, Shinagawa, Japan.
Mod Rheumatol Case Rep. 2021 Jul;5(2):347-353. doi: 10.1080/24725625.2021.1911426. Epub 2021 Apr 22.
Granulomatosis with polyangiitis is a systemic, small vessel vasculitis associated with the anti-neutrophil cytoplasmic antibody. We herein report a case of granulomatosis with polyangiitis with paravertebral lesions. A 69-year-old man presented to our hospital with fever, back pain, and myalgia. A computed tomography scan showed multiple lung nodules, while magnetic resonance imaging revealed soft tissue shadows around a thoracic vertebral lesion. A laboratory examination revealed positive myeloperoxidase anti-neutrophil cytoplasmic antibody. He was diagnosed with granulomatosis with polyangiitis. He was treated with oral glucocorticoid and intravenous cyclophosphamide, and the shadows resolved. Physicians should consider granulomatosis with polyangiitis in cases with paravertebral lesions.
肉芽肿性多血管炎是一种与抗中性粒细胞胞浆抗体相关的系统性小血管血管炎。本文报告 1 例伴椎旁病变的肉芽肿性多血管炎。1 例 69 岁男性因发热、背痛和肌痛就诊于我院。胸部 CT 扫描显示多个肺结节，磁共振成像显示胸椎体病变周围软组织影。实验室检查发现髓过氧化物酶抗中性粒细胞胞浆抗体阳性。诊断为肉芽肿性多血管炎。给予口服糖皮质激素和静脉环磷酰胺治疗，阴影消退。对于伴有椎旁病变的患者，医生应考虑肉芽肿性多血管炎。
