James and Carolyn Frenkil Dean's Professor and Chair, Department of Pharmacology, Director - Program in Neuroscience, University of Maryland School of Medicine, 685 West Baltimore Street, Baltimore MD, 21201, USA.
Neuron. 2021 Apr 21;109(8):1253-1254. doi: 10.1016/j.neuron.2021.04.004.
The neurobiology of sex differences in pain remain poorly understood. Yu et al. (2021) provide new insight by demonstrating that activation of dopaminergic projections from PAG to BNST provides substantial pain relief in male mice but virtually none in females.
性别的神经生物学基础对疼痛的影响仍知之甚少。Yu 等人（2021 年）通过实验发现，中脑导水管周围灰质到臂旁核的多巴胺能投射的激活能显著缓解雄性小鼠的疼痛，但对雌性小鼠几乎没有效果，为这一问题提供了新的见解。
