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到达目的地:甲状腺激素受体细胞内转运。

Getting there: Thyroid hormone receptor intracellular trafficking.

机构信息

Department of Biology, William & Mary, Williamsburg, Virginia, USA.

出版信息

J Biol Chem. 2021 Jan-Jun;296:100677. doi: 10.1016/j.jbc.2021.100677. Epub 2021 Apr 19.

Abstract

A year ago, when I first contemplated writing this article, my intent was to provide a detailed review of the contributions of the diverse community of talented scientists in my lab to the nuclear receptor research field. In the throes of a deadly pandemic, political turmoil, and Black Lives Matter, however, I found myself compelled to tell a more personal story. While I will still cover milestones in our understanding of the intracellular trafficking of the thyroid hormone receptor, now these will be set against the backdrop of my path as a woman in STEM and on being intentionally inclusive. By sharing reflections on my journey, I hope to encourage young investigators to persist in their pursuit of a career in science.

摘要

一年前,当我第一次考虑写这篇文章时,我的本意是详细回顾我实验室中才华横溢的科学家们在核受体研究领域的贡献。然而,在这场致命的大流行病、政治动荡和“黑人的命也是命”运动中,我发现自己不得不讲述一个更个人化的故事。虽然我仍将涵盖我们对甲状腺激素受体细胞内转运的理解的里程碑,但现在这些将以我作为女性在 STEM 领域的经历和有意包容的背景下呈现。通过分享我旅程中的思考,我希望鼓励年轻的研究人员坚持追求科学事业。

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