Department of General Surgery, The Second Hospital of Anhui Medical University, Hefei, Anhui, China.
Clinic for Organ Transplantation, The First Affiliated Hospital of University of Science and Technology of China, Hefei, Anhui, China.
Transplant Proc. 2021 May;53(4):1295-1299. doi: 10.1016/j.transproceed.2021.03.014. Epub 2021 Apr 20.
Hepatic artery thrombosis (HAT), a serious complication after orthotopic liver transplantation, almost always leads to morbidity and mortality without urgent revascularization or retransplantation, especially if HAT occurs within a few days after transplantation.
Herein we describe a case report of an orthotopic liver transplantation patient surviving without hepatic artery flow due to HAT on postoperative day 1. Reanastomosis, thrombectomy, and intra-arterial thrombolysis were performed, but only retrograde arterial flow by Doppler ultrasound, not by angiography, could be demonstrated in the hepatic artery. This case report is in compliance with the Declaration of Helsinki and the Declaration of Istanbul.
Based on the evidence from this patient, we believe that patients with failed revascularization can experience a long-term survival with conservative treatment. Retransplantation should be evaluated based on laboratory findings because graft function in individual patients can recover.
肝动脉血栓形成（HAT）是原位肝移植后的严重并发症，几乎总是导致发病率和死亡率，如果不进行紧急血运重建或再次移植，尤其是在移植后几天内发生 HAT 时更是如此。
本文描述了一例肝移植术后第 1 天发生 HAT 导致肝动脉血流中断的患者的病例报告。进行了再吻合、血栓切除术和动脉内溶栓治疗，但仅通过多普勒超声而非血管造影显示肝动脉存在逆行性动脉血流。本病例报告符合赫尔辛基宣言和伊斯坦布尔宣言。
基于该患者的证据，我们认为血管重建失败的患者可以通过保守治疗获得长期生存。应根据实验室检查结果评估再次移植，因为个别患者的移植物功能可以恢复。
