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确定可持续的生活方式策略以维持良好的血糖控制:定性研究结果的验证。

Identifying sustainable lifestyle strategies for maintaining good glycemic control: a validation of qualitative findings.

机构信息

Department of Preventive Medicine and Population Health, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA

Department of Preventive Medicine and Population Health, The University of Texas Medical Branch at Galveston, Galveston, Texas, USA.

出版信息

BMJ Open Diabetes Res Care. 2021 Apr;9(1). doi: 10.1136/bmjdrc-2020-002103.

Abstract

INTRODUCTION

Diabetes self-care practices are less effective outside of controlled research settings, and almost half of patients do not achieve good glycemic control. Qualitative studies suggest some lifestyle strategies may be linked to good control, but those strategies have not been validated. This study provides population-based evidence that dietary strategies identified in qualitative studies are associated with glycemic control in US patients with diabetes.

RESEARCH DESIGN AND METHODS

In a cross-sectional sample of the National Health and Nutrition Examination Survey (NHANES), qualitative self-management themes were matched to survey questions and used to predict good glycemic control (hemoglobin A1c <7.0% (53 mmol/mol)). Patients were limited to those 50 years of age and older with a diagnosis of diabetes for at least 1 year (N=465).

RESULTS

Patients averaged 65 years of age with a body mass index of 32.56 kg/m and 42% reported no physical activity. In logistic regression models controlling for sociodemographic and medical history variables, self-monitoring of blood glucose, weight loss, and physical activity were not significantly associated with glycemic control. Instead, dietary practices such as consuming low-calorie foods (OR=4.05, 95% CI 1.64 to 10.01), eating less fat (OR=2.15, 95% CI 1.03 to 4.47), and reducing sodium (OR=1.94, 95% CI 1.18 to 3.17) were significantly associated with good glycemic control, as was diabetes education or consultation with a dietitian (OR=3.48, 95% CI 1.28 to 9.45). Non-adherence to medications (OR=0.27, 95% CI 0.11 to 0.68) and general dietary descriptions, such as following a 'diabetic diet' (OR=0.32, 95% CI 0.17 to 0.57) and 'changing eating habits for weight loss' (OR=0.34, 95% CI 0.15 to 0.77), were associated with poorer glycemic control.

CONCLUSIONS

The NHANES validation of lifestyle management strategies suggests practices that may be sustainable. In a population that tends to be obese with low physical activity, successful self-care might emphasize specific dietary practices offering concrete touchpoints for patient communication and guidance. These strategies might help maintain glycemic control.

摘要

引言:糖尿病自我护理实践在受控研究环境之外效果较差,几乎有一半的患者无法达到良好的血糖控制。定性研究表明,一些生活方式策略可能与良好的控制有关,但这些策略尚未得到验证。本研究提供了基于人群的证据,表明在接受糖尿病治疗的美国患者中,定性研究中确定的饮食策略与血糖控制有关。

方法:在国家健康和营养检查调查(NHANES)的横断面样本中,将定性自我管理主题与调查问题相匹配,并用于预测良好的血糖控制(血红蛋白 A1c <7.0%(53 mmol/mol))。研究对象仅限于年龄在 50 岁及以上、糖尿病诊断至少 1 年(N=465)的患者。

结果:患者平均年龄为 65 岁,体重指数为 32.56kg/m,42%的患者没有体力活动。在控制社会人口统计学和病史变量的逻辑回归模型中,血糖自我监测、体重减轻和体力活动与血糖控制无显著相关性。相反,饮食行为,如食用低热量食物(OR=4.05,95%CI 1.64 至 10.01)、减少脂肪摄入(OR=2.15,95%CI 1.03 至 4.47)和减少钠摄入(OR=1.94,95%CI 1.18 至 3.17)与良好的血糖控制显著相关,糖尿病教育或与营养师咨询(OR=3.48,95%CI 1.28 至 9.45)也是如此。不遵医嘱服药(OR=0.27,95%CI 0.11 至 0.68)和一般饮食描述,如“遵循糖尿病饮食”(OR=0.32,95%CI 0.17 至 0.57)和“为减肥改变饮食习惯”(OR=0.34,95%CI 0.15 至 0.77)与较差的血糖控制有关。

结论:NHANES 对生活方式管理策略的验证表明,这些策略可能具有可持续性。在一个肥胖且体力活动水平低的人群中,成功的自我护理可能强调具体的饮食实践,为医患沟通和指导提供具体的切入点。这些策略可能有助于维持血糖控制。

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本文引用的文献

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6. Glycemic Targets: .6. 血糖目标: 。
Diabetes Care. 2020 Jan;43(Suppl 1):S66-S76. doi: 10.2337/dc20-S006.
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