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硬腭巨大刺激性纤维瘤:一种罕见临床实体的病例报告。

Large irritation fibroma of hard palate: a case report of a rare clinical entity.

机构信息

Department of Otorhinolaryngology, School of Medicine, University of Thessaly, Larissa, Greece.

Department of Otorhinolaryngology, 401 Army General Training Hospital, Athens, Greece.

出版信息

Pan Afr Med J. 2021 Jan 19;38:61. doi: 10.11604/pamj.2021.38.61.27662. eCollection 2021.

DOI:10.11604/pamj.2021.38.61.27662
PMID:33889227
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8028366/
Abstract

Fibromas are benign tumors of connective tissue common in the oral cavity but rare on hard palate. This paper reports on an asymptomatic, slowly growing mass on the hard palate of a 90-year-old lady, with a reported use of denture for two decades. The patient presented with a 2.2cm, smooth-surfaced, well-circumscribed nodule attached with a stalk to the palatal mucosa. After excision, the histopathological examination revealed a mass of fibrous connective tissue, covered by stratified squamous epithelium with focal low-medium grade hyperplasia and hyperkeratosis. These findings were consistent with irritation fibroma of hard palate, a rare entity, which should be considered as a possible diagnosis for tumors of the area by every physician.

摘要

纤维瘤是一种常见于口腔的良性结缔组织肿瘤,但在硬腭上很少见。本文报告了一例 90 岁女性硬腭上无症状、缓慢生长的肿块,该患者使用义齿已有 20 年。患者表现为 2.2cm 大、表面光滑、边界清楚的结节,附有一蒂与腭黏膜相连。切除后,组织病理学检查显示为纤维状结缔组织肿块,被复层鳞状上皮覆盖,有局灶性中-低度增生和角化过度。这些发现与硬腭刺激纤维瘤一致,这是一种罕见的实体,每个医生都应将其作为该区域肿瘤的可能诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/9d38fda9185d/PAMJ-38-61-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/7313d5100c95/PAMJ-38-61-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/cb476604c055/PAMJ-38-61-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/752b2189c579/PAMJ-38-61-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/32bf8f8bfac7/PAMJ-38-61-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/9d38fda9185d/PAMJ-38-61-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/7313d5100c95/PAMJ-38-61-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/cb476604c055/PAMJ-38-61-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/752b2189c579/PAMJ-38-61-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/32bf8f8bfac7/PAMJ-38-61-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e646/8028366/9d38fda9185d/PAMJ-38-61-g005.jpg

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引用本文的文献

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A Large Irritation Fibroma of the Hard Palate: A Rare Clinical Entity.硬腭巨大刺激性纤维瘤:一种罕见的临床实体。
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