Eigenmann J E, Amador A, Patterson D F
Department of Clinical Studies, School of Veterinary Medicine, University of Pennsylvania, Philadelphia.
Acta Endocrinol (Copenh). 1988 May;118(1):105-8. doi: 10.1530/acta.0.1180105.
Plasma insulin-like growth factor I concentrations from proportionate, chondrodystrophic and giant breeds were evaluated and compared with body size. IGF-I plasma concentrations were 91.2 +/- 10.9 micrograms/l in Keeshounds (proportionate dog), 122.6 +/- 25.4 micrograms/l in Bassethounds (chondrodystrophic dog) and 280 +/- 22.8 micrograms/l in German Shepherds (proportionate dog). The highest IGF-I level (389.6 +/- 24.2 micrograms/l) was found in the New Foundland, a giant breed (mean +/- SEM). The mean body weight was 11.8 +/- 0.4 kg in Keeshounds, 15.4 +/- 1.4 kg in Bassethounds, 32 +/- 1.5 kg in German Shepherds, and 45.6 +/- 1.7 kg in New Foundlands (mean +/- SEM). Body weight and plasma IGF-I concentration were significantly correlated (y (IGF-I) = -7.43 + 8.7 X (body weight); P less than 0.0001.
对体型匀称、软骨发育不良和大型犬种的血浆胰岛素样生长因子I浓度进行了评估，并与体型大小进行了比较。爱尔兰猎狼犬（体型匀称的犬种）的IGF-I血浆浓度为91.2±10.9微克/升，巴吉度猎犬（软骨发育不良的犬种）为122.6±25.4微克/升，德国牧羊犬（体型匀称的犬种）为280±22.8微克/升。在大型犬种纽芬兰犬中发现了最高的IGF-I水平（389.6±24.2微克/升）（均值±标准误）。爱尔兰猎狼犬的平均体重为11.8±0.4千克，巴吉度猎犬为15.4±1.4千克，德国牧羊犬为32±1.5千克，纽芬兰犬为45.6±1.7千克（均值±标准误）。体重与血浆IGF-I浓度显著相关（y（IGF-I）=-7.43 + 8.7X（体重）；P<0.0001）。
