Osterman P O, Fagius J, Säfwenberg J, Wikström B
Department of Neurology, University Hospital, Uppsala, Sweden.
Acta Neurol Scand. 1988 Apr;77(4):273-7. doi: 10.1111/j.1600-0404.1988.tb05909.x.
Symptoms reappeared within 2-4 weeks in 6 of 23 patients with acute Guillain-Barré syndrome who had demonstrated significant clinical improvement following plasma exchange therapy; all however improved to full recovery after a second series of plasma exchanges. The procedure appears to be associated with increased risk of early relapse. Our observations suggest that a relationship may exist between rapid removal of large amounts of plasma and the possibility of relapse.
23例急性吉兰-巴雷综合征患者在接受血浆置换治疗后临床症状显著改善，但其中6例在2 - 4周内症状复发；不过，所有患者在接受第二轮血浆置换后均完全康复。该治疗方法似乎与早期复发风险增加有关。我们的观察结果表明，大量血浆的快速清除与复发可能性之间可能存在关联。
