199168Medical Research Foundation of Trinidad and Tobago, Port of Spain, Trinidad.
Department of Paraclinical Sciences, University of the West Indies, St Augustine, Trinidad.
Int J STD AIDS. 2021 Aug;32(9):830-836. doi: 10.1177/0956462421997193. Epub 2021 Apr 23.
A chart review study was conducted to determine the prevalence of syphilis and explore the associated risk factors among men who have sex with men (MSM) who attended a large HIV clinic in Trinidad during the period January-December 2019. Patients were routinely screened for syphilis annually, and demographic, clinical, and laboratory data were extracted from the medical records. Descriptive and bivariate analyses were performed, and factors significantly associated with a syphilis diagnosis were assessed using multivariate logistic regression. During the period, 218 MSM were seen, age range 19-67 years, and median age 34.0 years. The prevalence of syphilis was 41.3% (90/218), and 71.1% (64//90) of these infections were asymptomatic. Multivariate analysis using logistic regression showed that MSM living with HIV in the 30-34 years old-age group (OR, 4.32; 95% CI, 1.04-18.02), and those with a previous history of treated syphilis (OR, 10.18; 95% CI, 4.60-22.53) were more likely to be diagnosed with syphilis. The prevalence of syphilis is high among MSM attending the HIV clinic in Trinidad, and most of these infections were asymptomatic; hence, targeted and sustained interventions to reduce syphilis transmission are urgently required. Repeat episodes of syphilis may play a role in the transmission dynamics of syphilis in MSM.
一项图表回顾研究旨在确定 2019 年 1 月至 12 月期间在特立尼达一家大型艾滋病毒诊所就诊的男男性行为者（MSM）中梅毒的流行情况，并探讨相关的危险因素。患者每年例行筛查梅毒，从病历中提取人口统计学、临床和实验室数据。进行描述性和双变量分析，并使用多变量逻辑回归评估与梅毒诊断显著相关的因素。在此期间，共观察到 218 名 MSM，年龄在 19-67 岁之间，中位年龄为 34.0 岁。梅毒的患病率为 41.3%（90/218），其中 71.1%（64/90）的感染为无症状。使用逻辑回归的多变量分析显示，年龄在 30-34 岁之间、同时患有艾滋病毒的 MSM（OR，4.32；95%CI，1.04-18.02），以及有既往治疗过的梅毒史的 MSM（OR，10.18；95%CI，4.60-22.53）更有可能被诊断为梅毒。在特立尼达的艾滋病毒诊所就诊的 MSM 中，梅毒的患病率很高，而且大多数感染都是无症状的；因此，迫切需要针对这些人群采取有针对性的和持续的干预措施来减少梅毒传播。梅毒的重复发作可能在 MSM 中梅毒传播的动态中起作用。
