Kerkhofs M, Kempenaers C, Linkowski P, de Maertelaer V, Mendlewicz J
Department of Psychiatry, Erasme Hospital, University of Brussels, Belgium.
Acta Psychiatr Scand. 1988 Apr;77(4):463-8. doi: 10.1111/j.1600-0447.1988.tb05152.x.
The effects of four subtypes of major depressive disorder on four sleep EEG variables obtained in 153 depressed inpatients were analyzed taking into account the effects of age, gender, DST response and severity of depression. We have found that age significantly affected slow wave sleep. Sleep efficiency and total sleep time were shown to vary with age and severity of depression. Such effects were not detected for REM latency which was influenced by the endogenous subtype and the gender. Our data indicate that in depressed patients sleep EEG measures are influenced by multiple factors.
在考虑年龄、性别、地塞米松抑制试验（DST）反应和抑郁严重程度的影响后，分析了153名住院抑郁症患者的四种主要抑郁症亚型对四个睡眠脑电图变量的影响。我们发现年龄对慢波睡眠有显著影响。睡眠效率和总睡眠时间显示随年龄和抑郁严重程度而变化。对于快速眼动睡眠潜伏期未检测到此类影响，其受内源性亚型和性别的影响。我们的数据表明，在抑郁症患者中，睡眠脑电图测量受多种因素影响。
