Macklis Paul C, Tyler Kelly, Kaffenberger Jessica, Kwatra Shawn, Kaffenberger Benjamin H
The Ohio State University College of Medicine, Columbus, OH, USA.
Division of Dermatology, Department of Internal Medicine, The Ohio State University Wexner Medical Center, 2012 Kenny Road, Rm 232, Columbus, OH, 43212, USA.
Arch Dermatol Res. 2022 Apr;314(3):293-300. doi: 10.1007/s00403-021-02233-y. Epub 2021 Apr 23.
Hidradenitis suppurativa (HS) is a chronic, inflammatory skin condition that substantially reduces patient quality of life. Many HS patients ask their dermatologist about potential lifestyle modifications, such as following particular diets or avoiding specific products, in an attempt to alleviate their symptoms. However, insufficient research has been conducted to support well-informed lifestyle modification counseling, and patients frequently defer to anecdotal endorsements of various interventions found on social media support groups. Therefore, we sought to clarify what lifestyle modifications were capable of improving HS symptoms.
We conducted a survey-based study to examine modifiable risk factors and their association with the severity of HS. Five hundred and ninety-one patients with HS participated in an online survey detailing the severity of their HS symptoms before and after various lifestyle interventions. Average improvements in both subjective and objective ratings of symptom severity were calculated and statistical differences between the levels of improvement seen among various categories of lifestyle interventions were determined.
Numerous lifestyle interventions including substantial weight loss, smoking cessation, use of gentle skin and depilatory products, and menstrual regulation were associated with both subjective and objective improvements in symptom severity.
Our results suggest that patients affected by HS may experience clinically significant improvement from a variety of lifestyle modifications.
化脓性汗腺炎（HS）是一种慢性炎症性皮肤病，会显著降低患者的生活质量。许多HS患者会向皮肤科医生咨询潜在的生活方式改变，比如遵循特定饮食或避免使用特定产品，以试图缓解症状。然而，目前尚未进行充分的研究来支持提供充分信息的生活方式改变咨询，患者常常依赖于在社交媒体支持群组中找到的各种干预措施的传闻推荐。因此，我们试图阐明哪些生活方式改变能够改善HS症状。
我们进行了一项基于调查的研究，以检查可改变的风险因素及其与HS严重程度的关联。591名HS患者参与了一项在线调查，详细说明了他们在各种生活方式干预前后HS症状的严重程度。计算了症状严重程度主观和客观评分的平均改善情况，并确定了各类生活方式干预之间改善水平的统计差异。
包括大幅减重、戒烟、使用温和的皮肤和脱毛产品以及月经调节在内的多种生活方式干预与症状严重程度的主观和客观改善均相关。
我们的结果表明，受HS影响的患者可能会通过多种生活方式改变在临床上获得显著改善。
