School of Dentistry, The University of Queensland, Brisbane, Qld, Australia.
School of Pharmacy, The University of Queensland, Brisbane, Qld, Australia.
Aust Dent J. 2021 Mar;66 Suppl 1:S37-S41. doi: 10.1111/adj.12846. Epub 2021 May 7.
Prescribing of antibiotics by dentists for surgical prophylaxis or as an adjunct to managing dental infections is a substantial part of the overall landscape for prescribed antibiotics in health care settings.
We explored trends in the antibiotic prescribing patterns of Australian dentists over the 12-year period, 2005-2016. We obtained data on dispensed prescriptions of antibiotics from registered dentists subsidized on the Pharmaceutical Benefits Scheme.
Australian dentists were responsible for almost 7 million dispensed prescriptions of antibiotics over 12 years; an average of 24 prescriptions per year per dentist. The most commonly prescribed antibiotic was amoxicillin, followed by amoxicillin + clavulanic acid and metronidazole. These top three antibiotics constituted more than 80% of all antibiotics prescribed and their use increased dramatically over time. There was a large increase in the prescribing of broad-spectrum antibiotics over time, most of which occurred from 2011 to 2016.
Excessive prescribing of broad-spectrum antibiotics runs contrary to national antimicrobial stewardship (AMS) initiatives and guidelines. Multifaceted educational strategies are essential to align prescribing with current best practice. High-level evidence to inform clear guidelines on antibiotic prescribing in dental infections, with audit and feedback, should reduce the inappropriate use of antibiotics in dentistry.
牙医开具抗生素用于手术预防或作为治疗口腔感染的辅助药物,这是医疗保健环境中规定使用抗生素的重要组成部分。
我们探讨了澳大利亚牙医在 2005 年至 2016 年 12 年间的抗生素处方模式趋势。我们从注册牙医开具的处方中获取了在药品福利计划下配药的抗生素数据。
在 12 年期间,澳大利亚牙医开具了近 700 万张抗生素处方,平均每位牙医每年开具 24 张处方。最常开的抗生素是阿莫西林,其次是阿莫西林+克拉维酸和甲硝唑。这三种抗生素占所有开处方抗生素的 80%以上,其使用量随着时间的推移显著增加。广谱抗生素的使用量也在增加,大部分增加发生在 2011 年至 2016 年期间。
过度开具广谱抗生素与国家抗菌药物管理(AMS)计划和指南背道而驰。多方面的教育策略对于使处方与当前最佳实践保持一致至关重要。提供明确的口腔感染抗生素处方指南,并进行审核和反馈,以提供高质量证据,应可减少牙科抗生素的不当使用。