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母乳喂养期间饮酒和吸烟与自闭症谱系障碍或注意缺陷多动障碍风险的关系。

Alcohol and Tobacco use While Breastfeeding and Risk of Autism Spectrum Disorder or Attention Deficit/Hyperactivity Disorder.

机构信息

Department of Psychology, Faculty of Medicine, Health and Human Sciences, Macquarie University, Balaclava Road, North Ryde, Sydney, NSW, 2109, Australia.

出版信息

J Autism Dev Disord. 2022 Mar;52(3):1223-1234. doi: 10.1007/s10803-021-05027-3. Epub 2021 Apr 24.

Abstract

Research has linked prenatal alcohol and tobacco use with Attention Deficit Hyperactivity Disorder (ADHD), and variably with Autism Spectrum Disorder (ASD). Lactational use has been scantly considered. This study examined whether it may alter ADHD or ASD risk. Participants were 5107 infants recruited in 2004 and assessed longitudinally for the Growing Up in Australia Study. Logistic regression did not find any associations between maternal alcohol and tobacco use while breastfeeding and ADHD or ASD diagnosis at ages 6-7 or 10-11 years. Alcohol and tobacco use during lactation may not increase ADHD or ASD risk. Abstaining from alcohol and tobacco, however, may still be the safest option. Analyses were limited by lack of alcohol timing and retrospective variables that future research should address.

摘要

研究表明,产前饮酒和吸烟与注意力缺陷多动障碍(ADHD)有关,与自闭症谱系障碍(ASD)也有关系。但哺乳期的饮酒问题则很少被考虑。本研究旨在探讨哺乳期饮酒是否会改变 ADHD 或 ASD 的风险。参与者为 2004 年招募的 5107 名婴儿,并在澳大利亚成长研究中进行了纵向评估。逻辑回归未发现母亲母乳喂养期间饮酒和吸烟与 6-7 岁或 10-11 岁时 ADHD 或 ASD 诊断之间存在任何关联。哺乳期饮酒和吸烟可能不会增加 ADHD 或 ASD 的风险。然而,戒酒和戒烟可能仍然是最安全的选择。但由于缺乏酒精摄入时间和回顾性变量的限制,未来的研究应该解决这些问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ce2c/8067780/19a3404d74c3/10803_2021_5027_Fig1_HTML.jpg

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