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标准饮食和高脂饮食在链脲佐菌素诱导的糖尿病大鼠模型中对并发症发展的影响。

Effect of Standard and High-Fat Diets during Modeling of Streptozotocin-Induced Diabetes in Rats on the Development of Complications.

机构信息

Affiliated Branch of M. M. Shemyakin and Y. A. Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Pushchino, Moscow region, Russia.

出版信息

Bull Exp Biol Med. 2021 Apr;170(6):737-740. doi: 10.1007/s10517-021-05144-0. Epub 2021 Apr 24.

DOI:10.1007/s10517-021-05144-0
PMID:33893947
Abstract

For evaluation of the effect of high-fat diet on the development of diabetic complications, the rats were maintained on standard or high-fat diet. In 3 weeks, diabetes mellitus was modeled by single intraperitoneal injection of streptozotocin. Changes in hematological parameters, physical and biochemical parameters of the urine, and in the development of thermal allodynia were different after 15-week standard and high-fat diets.

摘要

为了评估高脂肪饮食对糖尿病并发症发展的影响，将大鼠维持在标准或高脂肪饮食中。在 3 周内，通过单次腹腔注射链脲佐菌素建立糖尿病模型。15 周标准和高脂肪饮食后，血液学参数、尿液的理化参数以及热感觉过敏的发展变化不同。

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本文引用的文献

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High-fat diet and streptozotocin in the induction of type 2 diabetes mellitus: a new proposal.高脂肪饮食与链脲佐菌素诱导2型糖尿病：一项新提议。
An Acad Bras Cienc. 2019 Mar 21;91(1):e20180314. doi: 10.1590/0001-3765201920180314.
2
Characterisation of pain responses in the high fat diet/streptozotocin model of diabetes and the analgesic effects of antidiabetic treatments.糖尿病高脂饮食/链脲佐菌素模型中疼痛反应的特征及抗糖尿病治疗的镇痛作用。
J Diabetes Res. 2015;2015:752481. doi: 10.1155/2015/752481. Epub 2015 Feb 9.
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The characterization of high-fat diet and multiple low-dose streptozotocin induced type 2 diabetes rat model.
脂质过氧化产物和抗氧化酶在猫无菌性和脓性炎症发病机制中的作用。
J Adv Vet Anim Res. 2021 Jun 17;8(2):210-217. doi: 10.5455/javar.2021.h504. eCollection 2021 Jun.
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Search for Promising Strains of Probiotic Microbiota Isolated from Different Biotopes of Healthy Cats for Use in the Control of Surgical Infections.寻找从健康猫的不同生物群落中分离出的有前景的益生菌微生物菌株，用于控制手术感染。
Pathogens. 2021 May 28;10(6):667. doi: 10.3390/pathogens10060667.
高脂饮食联合多次低剂量链脲佐菌素诱导的2型糖尿病大鼠模型的表征
Exp Diabetes Res. 2008;2008:704045. doi: 10.1155/2008/704045. Epub 2009 Jan 4.