Department of Otolaryngology, University of Colorado, Denver, Colorado, U.S.A.
Laryngoscope. 2021 Oct;131(10):E2676-E2680. doi: 10.1002/lary.29585. Epub 2021 Apr 24.
This study aimed to add to the body of evidence for efficacy of Superior Laryngeal Nerve (SLN) blocks for treatment of neurogenic cough. Efficacy at short- and long-term intervals are presented as well as relationships with laryngoscopic findings.
A retrospective chart review of patients treated with SLN block between 2018 and 2020 was conducted. Patient demographics, videostroboscopic findings, and patient-subjective perception of outcomes were recorded and analyzed. Cough Severity Index (CSI) scores from pre-injection, short-term follow-up, and long-term follow-up were compared.
Twenty patients underwent SLN block in the clinic setting. Four patients were excluded for incomplete records. The indication was neurogenic cough refractory to medical management and/or cough suppression therapy. Patients with short-term follow-up (n = 13) had statistically significant decrease in CSI scores, with a mean baseline CSI of 24.3 decreasing to 16.15 (P = .006). Patients with evidence of Vocal Fold Motion/Vibratory Abnormalities (VFA) (n = 8) showed improvement in short-term CSI scores, with a mean baseline CSI of 24.13 decreasing to 14.5 (P = .004). Those without evidence of VFA did not have statistically significant improvement in short-term CSI scores. At long-term follow-up, patients with VFA had improvements that approached statistical significance with a mean baseline CSI of 22.56 decreasing to 14.56 (P = .057), while patients without VFA showed no improvement.
Our results are consistent with previous literature indicating efficacy of SLN block. The presence of VFA may be an indicator of patients who experience increased therapeutic effect.
4 Laryngoscope, 131:E2676-E2680, 2021.
本研究旨在为治疗神经性咳嗽的喉上神经(SLN)阻滞的疗效提供更多证据。本文介绍了短期和长期疗效以及与喉镜检查结果的关系。
对 2018 年至 2020 年期间接受 SLN 阻滞治疗的患者进行回顾性图表审查。记录并分析了患者的人口统计学资料、频闪喉镜检查结果以及患者对治疗结果的主观感知。比较了注射前、短期随访和长期随访的咳嗽严重程度指数(CSI)评分。
20 例患者在诊所接受了 SLN 阻滞。由于记录不完整,有 4 例患者被排除在外。适应证为对药物治疗和/或咳嗽抑制治疗无效的神经性咳嗽。有短期随访的患者(n=13)CSI 评分有显著下降,基线 CSI 平均为 24.3 降至 16.15(P=0.006)。有声带运动/振动异常(VFA)证据的患者(n=8)短期 CSI 评分改善,基线 CSI 平均为 24.13 降至 14.5(P=0.004)。无 VFA 证据的患者短期 CSI 评分无显著改善。长期随访时,有 VFA 的患者 CSI 评分有显著改善,基线 CSI 平均为 22.56 降至 14.56(P=0.057),而无 VFA 的患者则无改善。
我们的结果与先前的文献一致,表明 SLN 阻滞有效。VFA 的存在可能是患者治疗效果增加的指标。
4 级喉镜,131:E2676-E2680,2021 年。