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喉上神经阻滞治疗慢性神经性咳嗽的纵向随访

Longitudinal Follow-up of Superior Laryngeal Nerve Block for Chronic Neurogenic Cough.

作者信息

Dhillon Vaninder K

机构信息

Division of Laryngology, Department of Head and Neck Surgery, Johns Hopkins University, Bethesda, Maryland, USA.

出版信息

OTO Open. 2021 Feb 16;5(1):2473974X21994468. doi: 10.1177/2473974X21994468. eCollection 2021 Jan-Mar.

Abstract

OBJECTIVE

To demonstrate longitudinal follow-up for patients who underwent in-office superior laryngeal nerve (SLN) block with lidocaine and steroids for chronic neurogenic cough.

STUDY DESIGN

Longitudinal follow-up study over 10 months.

SETTING

Clinical.

METHODS

A retrospective review of 30 patients who underwent in-office nerve block to the SLN for neurogenic cough, including the 10 patients whose outcomes were originally published in 2019.

RESULTS

Thirty patients in this study who underwent a series of SLN blocks showed significant improvement in cough severity index (CSI). The average number of blocks was 3 (range, 2-8). Twelve patients underwent initial SLN block to the left side and 18 patients underwent initial SLN block to the right side. The mean follow-up from the first SLN block was 5.3 months. The mean pretreatment and posttreatment CSI scores were 27 and 11, respectively, for all 30 patients who underwent an SLN block. A Wilcoxon signed rank test shows that there is a significant effect on CSI ( = 2, = -4.659, < .05). The mean longitudinal follow-up for the original 10 patients was 10 months from the first SLN block, with none of these patients receiving any further treatment for their cough.

CONCLUSION

Superior laryngeal nerve block is an effective long-term treatment for neurogenic cough. No additional treatment was required within 10 months of the SLN block.

LEVEL OF EVIDENCE

Level IV.

摘要

目的

对接受利多卡因和类固醇药物的门诊喉上神经(SLN)阻滞治疗慢性神经性咳嗽的患者进行纵向随访。

研究设计

为期10个月的纵向随访研究。

研究地点

临床。

方法

回顾性分析30例因神经性咳嗽接受门诊SLN阻滞治疗的患者,其中包括10例其结果最初于2019年发表的患者。

结果

本研究中接受一系列SLN阻滞的30例患者咳嗽严重程度指数(CSI)有显著改善。平均阻滞次数为3次(范围为2 - 8次)。12例患者首次接受左侧SLN阻滞,18例患者首次接受右侧SLN阻滞。首次SLN阻滞后的平均随访时间为5.3个月。所有30例接受SLN阻滞的患者治疗前和治疗后的CSI评分分别为27分和11分。Wilcoxon符号秩检验显示对CSI有显著影响( = 2, = -4.659, <.05)。最初10例患者从首次SLN阻滞后的平均纵向随访时间为10个月,这些患者中没有一人因咳嗽接受任何进一步治疗。

结论

喉上神经阻滞是治疗神经性咳嗽的一种有效的长期治疗方法。在SLN阻滞后10个月内无需额外治疗。

证据级别

IV级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/370c/7890738/2e45fe0abc2a/10.1177_2473974X21994468-fig1.jpg

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