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喉上神经阻滞治疗神经性咳嗽:病例系列

Superior laryngeal nerve block for neurogenic cough: A case series.

作者信息

Dhillon Vaninder K

机构信息

Division of Laryngology, Department of Head and Neck Surgery Johns Hopkins University Bethesda Maryland U.S.A.

出版信息

Laryngoscope Investig Otolaryngol. 2019 Jul 5;4(4):410-413. doi: 10.1002/lio2.292. eCollection 2019 Aug.

DOI:10.1002/lio2.292
PMID:31453350
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6703134/
Abstract

OBJECTIVES

To demonstrate that an in-office superior laryngeal nerve (SLN) block with lidocaine and steroids is an effective alternative to neuromodulators for patients with neurogenic cough.

STUDY DESIGN

Retrospective study.

METHODS

A retrospective review of 10 patients who underwent in office nerve block to the laryngeal nerve (SLN) for neurogenic cough. Demographic data and pre- and postcough survey index are the measure outcomes. Follow-up was 3-6 months.

RESULTS

We find that all patients in this study that underwent an SLN block showed significant improvement in cough severity index (CSI). The average number of blocks was 2.3. The mean follow-up time from the first SLN block is 3.4 months. The mean CSI improvement 16.30. 95% confidence interval, 11.44-21.16;  < .0001. All patients in this study completed at least one session of cough suppression therapy with speech language pathology (SLP). No patients were on neuromodulators at the time of the SLN block.

CONCLUSIONS

There is a role for in-office SLN block with lidocaine and steroids for patients with neurogenic cough, and can be an effective alternative to neuromodulators.

LEVEL OF EVIDENCE

NA.

摘要

目的

证明利多卡因和类固醇的门诊喉上神经(SLN)阻滞是神经源性咳嗽患者神经调节剂的有效替代方法。

研究设计

回顾性研究。

方法

回顾性分析10例因神经源性咳嗽接受门诊喉上神经阻滞的患者。人口统计学数据以及咳嗽前后的调查指标为测量结果。随访时间为3至6个月。

结果

我们发现本研究中所有接受SLN阻滞的患者咳嗽严重程度指数(CSI)均有显著改善。平均阻滞次数为2.3次。首次SLN阻滞的平均随访时间为3.4个月。CSI平均改善16.30。95%置信区间为11.44 - 21.16;P < 0.0001。本研究中的所有患者均至少完成了一次言语语言病理学(SLP)咳嗽抑制治疗。在进行SLN阻滞时,没有患者使用神经调节剂。

结论

利多卡因和类固醇的门诊SLN阻滞对神经源性咳嗽患者有作用,并且可以成为神经调节剂的有效替代方法。

证据级别

无。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6600/6703134/dfed74aeeff4/LIO2-4-410-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6600/6703134/dfed74aeeff4/LIO2-4-410-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6600/6703134/dfed74aeeff4/LIO2-4-410-g001.jpg

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3
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5
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6
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7
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10
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5
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J Voice. 2015 Nov;29(6):763-7. doi: 10.1016/j.jvoice.2015.01.001. Epub 2015 Mar 17.
7
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Laryngoscope. 2013 Aug;123(8):1931-6. doi: 10.1002/lary.23916. Epub 2013 Jun 4.
9
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10
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Cough. 2010 Jul 28;6:5. doi: 10.1186/1745-9974-6-5.