University Clinic of Cardiology, University of Ss. Cyril and Methodius, Faculty of Medicine Skopje, North Macedonia.
College of Medicine and Health Sciences, Al Ain, UAE.
Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2021 Apr 23;42(1):53-66. doi: 10.2478/prilozi-2021-0004.
: The aim of this paper is to indicate if carotid stenosis is predictive for the prognosis of coronary artery disease.: Our study is a prospective cohort study. 1031 patients with proven coronary artery disease (CAD) were recruited consecutively. Carotid ultrasound was used to assess IMT, plaque, or stenosis. They were followed for 24 months for adverse cardiovascular events. Selected demographic date such as smoking history, dyslipidemia, hypertension, laboratory values, and clinical data (associated diseases and risk) were collected from each patient. Total cardiovascular events and mortality rate were followed up for the study population. The results were collected prospectively and retrospectively. The study was organized as a clinical, cross-sectional study and comparative study.From the data collected with the clinical research, a file was formed in the statistical program with the help of which the data were statistically analyzed.From the methods of descriptive statistics, absolute frequencies, percentages, arithmetic mean, median, measures of variability, minimum, maximum, standard deviation and logistic regression models were used.: Of the total number of patients 1026 had arterial hypertension (HTA). Data on hyperlipidemia (HLP) had been reported in 895 patients. 1.023 patients had peripheral artery disease (PAB). 1031 patients were presented with multivessel coronary artery disease (CAD). There were 1,029 patients with diabetes mellitus (DM), while 1,013 patients had coronary artery by-pass (CABG), and 1,012 had stroke (CVI). Elevated systolic blood pressure was reported in 966 patients. 184 patients had elevated triglycerides and 187 had elevated cholesterol. 1,008 patients have had a history of myocardial infarction. Carotid artery stenosis (CAS) has been found in 1,009 patients, increased body mass index (BMI) in 270 patients.1.031 patients were followed for 24 months. Cardiovascular events were reported in 54 patients (or 5.2%). Revascularization was performed in 28 (4.1%) patients, while 12 (1.8%) of patients died. Diabetes mellitus (OR 1.878 95% CI 0.491 7.184) and Carotid stenosis (OR 2.185 95% CI 0.731 6.53) were found to be predictive factors for future cardiovascular events.: Due to our results carotid ultrasound may be a useful tool for risk stratification of coronary artery disease pts.
: 本文旨在探讨颈动脉狭窄是否对冠状动脉疾病的预后具有预测价值。: 本研究为前瞻性队列研究。连续招募了 1031 例经证实的冠状动脉疾病（CAD）患者。采用颈动脉超声评估 IMT、斑块或狭窄情况。对患者进行了 24 个月的随访，以观察不良心血管事件的发生情况。从每位患者收集了选定的人口统计学数据，如吸烟史、血脂异常、高血压、实验室值和临床数据（相关疾病和风险）。总心血管事件和死亡率为研究人群进行了随访。结果进行了前瞻性和回顾性收集。该研究组织为临床横断面研究和比较研究。通过临床研究收集的数据，在统计程序的帮助下形成了一个文件，通过该文件对数据进行了统计分析。采用描述性统计、绝对频率、百分比、算术平均值、中位数、变异性指标、最小值、最大值、标准差和逻辑回归模型等方法。在总共 1031 例患者中，有 1026 例患有动脉高血压（HTA）。在 895 例患者中报告了高脂血症（HLP）的数据。1023 例患者患有外周动脉疾病（PAB）。1031 例患者患有多支冠状动脉疾病（CAD）。有 1029 例患者患有糖尿病（DM），有 1013 例患者进行了冠状动脉旁路移植术（CABG），有 1012 例患者发生了中风（CVI）。966 例患者的收缩压升高。184 例患者的甘油三酯升高，187 例患者的胆固醇升高。1008 例患者有心肌梗死病史。在 1009 例患者中发现了颈动脉狭窄（CAS），在 270 例患者中发现了体重指数（BMI）升高。对 1031 例患者进行了 24 个月的随访。54 例患者（或 5.2%）报告了心血管事件。对 28 例（4.1%）患者进行了血运重建，12 例（1.8%）患者死亡。糖尿病（OR 1.878 95% CI 0.491 7.184）和颈动脉狭窄（OR 2.185 95% CI 0.731 6.53）被发现是未来心血管事件的预测因素。: 由于我们的结果，颈动脉超声可能是冠状动脉疾病患者风险分层的有用工具。
