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仅报告相对效应度量可能具有误导性:一些改进流行病学结果可靠性的良好实践。

Reporting only relative effect measures was potentially misleading: some good practices for improving the soundness of epidemiological results.

机构信息

Department of Statistical Sciences "Paolo Fortunati", University of Bologna, Bologna, Italy.

Department of Statistical Sciences "Paolo Fortunati", University of Bologna, Bologna, Italy.

出版信息

J Clin Epidemiol. 2021 Sep;137:195-199. doi: 10.1016/j.jclinepi.2021.04.006. Epub 2021 Apr 21.

Abstract

OBJECTIVE

In the medical and epidemiological literature there is a growing tendency to report an excessive number of decimal digits (often three, sometimes four), especially when measures of relative occurrence are small; this can be misleading.

STUDY DESIGN AND SETTING

We combined mathematical and statistical reasoning about the precision of relative risks with the meaning of the decimal part of the same measures from biological and public health perspectives.

RESULTS

We identified a general rule for minimizing the mathematical error due to rounding of relative risks, depending on the background absolute rate, which justifies the use of one or more decimal digits for estimates close to 1.

CONCLUSIONS

We suggest that both relative and absolute risk measures (expressed as a rates) should be reported, and two decimal digits should be used for relative risk close to 1 only if the background rate is at least 1/1,000 py. The use of more than two decimal digits is justified only when the background rate is high (ie, 1/10 py).

摘要

目的

在医学和流行病学文献中,报告过多的小数位数(通常为三位,有时为四位)的趋势越来越明显,尤其是当相对发生率较小时;这可能会产生误导。

研究设计和环境

我们结合了相对风险的精度的数学和统计推理,以及从生物学和公共卫生角度来看相同测量值的小数部分的含义。

结果

我们确定了一种最小化因四舍五入导致的相对风险的数学误差的通用规则,该规则取决于背景绝对率,这证明了在接近 1 的估计值使用一位或多位小数是合理的。

结论

我们建议报告相对和绝对风险测量值(表示为率),并且只有当背景率至少为 1/1,000 py 时,接近 1 的相对风险才使用两位小数。只有当背景率较高(即 1/10 py)时,使用超过两位小数才有意义。

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