Department of Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.
Robert Wood Johnson Medical School, Rutgers University, New Brunswick, New Jersey, USA.
World Neurosurg. 2021 Jul;151:e426-e437. doi: 10.1016/j.wneu.2021.04.050. Epub 2021 Apr 21.
The medial occipital lobe, composed of the lingual gyrus and cuneus, is necessary for both basic and higher level visual processing. It is also known to facilitate cross-modal, nonvisual functions, such as linguistic processing and verbal memory, after the loss of the visual senses. A detailed cortical model elucidating the white matter connectivity associated with this area could improve our understanding of the interacting brain networks that underlie complex human processes and postoperative outcomes related to vision and language.
Generalized q-sampling imaging tractography, validated by gross anatomic dissection for qualitative visual agreement, was performed on 10 healthy adult controls obtained from the Human Connectome Project.
Major white matter connections were identified by tractography and validated by gross dissection, which connected the medial occipital lobe with itself and the adjacent cortices, especially the temporal lobe. The short- and long-range connections identified consisted mainly of U-shaped association fibers, intracuneal fibers, and inferior fronto-occipital fasciculus, inferior longitudinal fasciculus, middle longitudinal fasciculus, and lingual-fusiform connections.
The medial occipital lobe is an extremely interconnected system, supporting its ability to perform coordinated basic visual processing, but also serves as a center for many long-range association fibers, supporting its importance in nonvisual functions, such as language and memory. The presented data represent clinically actionable anatomic information that can be used in multimodal navigation of white matter lesions in the medial occipital lobe to prevent neurologic deficits and improve patients' quality of life after cerebral surgery.
由舌回和楔叶组成的枕中回是进行基本和高级视觉处理所必需的。在视觉丧失后，它也有助于跨模态的非视觉功能，如语言处理和言语记忆。详细的皮质模型阐明与该区域相关的白质连接，可以提高我们对相互作用的大脑网络的理解，这些网络是与视觉和语言相关的复杂人类过程和术后结果的基础。
在 10 名来自人类连接组计划的健康成年对照者中，使用广义 q 采样成像纤维追踪技术（通过大体解剖进行定性视觉验证）进行研究。
通过纤维追踪术确定了主要的白质连接，并通过大体解剖进行了验证，这些连接将枕中回与自身和相邻皮质，特别是颞叶连接起来。确定的短程和长程连接主要由 U 形联合纤维、内楔纤维和下额枕束、下纵束、中纵束和舌状回纤维组成。
枕中回是一个极其相互连接的系统，支持其进行协调的基本视觉处理的能力，但也是许多长程联合纤维的中心，支持其在非视觉功能（如语言和记忆）中的重要性。所呈现的数据代表了可用于临床的解剖学信息，可用于内侧枕叶白质病变的多模态导航，以预防神经功能缺损并提高患者脑手术后的生活质量。
