Young R H
James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Boston 02114.
Am J Surg Pathol. 1988 Jul;12(7):542-6. doi: 10.1097/00000478-198807000-00005.
Eight patients from 20 months to 79 years of age (average, 49 years) with papillary or polypoid inflammatory lesions of the urinary bladder were studied. On cystoscopic examination or initial pathologic examination, several of the lesions were thought to be neoplasms. Their clinical and pathologic features, however, were typical for papillary and polypoid cystitis. Microscopic examination disclosed thin, finger-like papillae or broad-based polypoid lesions with prominent stromal edema typically associated with chronic inflammation. The lesions were covered by, and adjacent to, urothelium that was usually normal but was occasionally metaplastic. A history of recent catheterization was present in only one case. These cases illustrate that occasional papillary or polypoid urothelial lesions are inflammatory rather than neoplastic.
对8例年龄在20个月至79岁(平均49岁)之间、患有膀胱乳头状或息肉状炎性病变的患者进行了研究。在膀胱镜检查或初次病理检查时,部分病变被认为是肿瘤。然而,它们的临床和病理特征是乳头状和息肉状膀胱炎的典型表现。显微镜检查发现有纤细的指状乳头或基底较宽的息肉状病变,伴有明显的间质水肿,这通常与慢性炎症有关。病变表面及周围被覆的尿路上皮通常正常,但偶尔会发生化生。仅1例有近期导尿史。这些病例表明,偶尔出现的乳头状或息肉状尿路上皮病变是炎性的而非肿瘤性的。