Departments of Surgery and Emergency Medicine, University of Southern California, Los Angeles, CA.
Departments of Surgery and Emergency Medicine, University of Southern California, Los Angeles, CA.
J Am Coll Surg. 2021 Aug;233(2):233-239.e2. doi: 10.1016/j.jamcollsurg.2021.03.023. Epub 2021 Apr 22.
Recent trends in prehospital tourniquet use remain underreported. In addition, the impact of prehospital tourniquet use on patient survival has not been evaluated in a population-level study. We hypothesized that prehospital tourniquets were used more frequently in Los Angeles County and their use was associated with improved patient survival.
This is a retrospective cohort study using a database maintained by the Los Angeles County Emergency Medical Services Agency. We included patients who sustained extremity vascular injuries between October 2015 and July 2019. Patients were divided into the following study groups: prehospital tourniquet and no-tourniquet group. Our primary end point was in-hospital mortality. The secondary outcomes included 4- and 24-hour transfusion requirements and delayed amputation.
A total of 944 patients met our inclusion criteria. Of those, 97 patients (10.3%) had prehospital tourniquets placed. The rate of tourniquet use increased linearly throughout our study period (goodness of fit, p = 0.014). In multivariable analysis, prehospital tourniquet use was significantly associated with improved mortality (adjusted odds ratio 0.32; 95% CI, 0.16 to 0.85; p = 0.032). Similarly, transfusion requirements were significantly lower within 4 hours (regression coefficient -547.76; 95% CI, -762.73 to -283.49; p < 0.001) and 24 hours (regression coefficient -1,389.82; 95% CI, -1,824.88 to -920.97; p < 0.001). There was no significant difference in delayed amputation rates (adjusted odds ratio 1.07; 95% CI, 0.21 to 10.88; p < 0.097).
Prehospital tourniquet use has been on the rise in Los Angeles County. Our results suggest that the use of prehospital tourniquets for extremity vascular injuries is associated with improved patient survival and decreased blood transfusion requirements, without an increase in delayed amputations.
最近的研究表明,在院前环境中使用止血带的情况仍未得到充分报告。此外,在人群水平的研究中,尚未评估院前使用止血带对患者生存的影响。我们假设在洛杉矶县,院前使用止血带的频率更高,并且与患者生存率的提高有关。
这是一项使用洛杉矶县紧急医疗服务局维护的数据库进行的回顾性队列研究。我们纳入了 2015 年 10 月至 2019 年 7 月期间发生四肢血管损伤的患者。患者被分为以下研究组:院前使用止血带组和未使用止血带组。我们的主要终点是院内死亡率。次要结局包括 4 小时和 24 小时的输血需求以及延迟性截肢。
共有 944 名患者符合纳入标准。其中,97 名患者(10.3%)在院前使用了止血带。止血带的使用率在整个研究期间呈线性增加(拟合优度,p = 0.014)。多变量分析显示,院前使用止血带与死亡率降低显著相关(调整优势比 0.32;95%置信区间,0.16 至 0.85;p = 0.032)。同样,4 小时内(回归系数-547.76;95%置信区间,-762.73 至-283.49;p < 0.001)和 24 小时内(回归系数-1389.82;95%置信区间,-1824.88 至-920.97;p < 0.001)的输血需求显著降低。延迟性截肢率无显著差异(调整优势比 1.07;95%置信区间,0.21 至 10.88;p < 0.097)。
在洛杉矶县,院前使用止血带的情况呈上升趋势。我们的研究结果表明,在四肢血管损伤患者中使用院前止血带与患者生存率的提高和输血需求的减少有关,而不会增加延迟性截肢的发生。