Master's and Doctoral Programs in Physical Therapy, City University of São Paulo (UNICID), São Paulo, São Paulo, Brazil.
Physioterapeutics Resources Laboratory, Department of Physical Therapy, Federal University of São Carlos (UFSCar), São Carlos, São Paulo, Brazil.
Clin Rehabil. 2021 Oct;35(10):1413-1427. doi: 10.1177/02692155211012004. Epub 2021 Apr 26.
To evaluate the effects of interferential current and photobiomodulation in patients with knee osteoarthritis.
A randomized, placebo-controlled, double-blind clinical trial.
Physiotherapy Clinic of City University of São Paulo.
A total of 184 patients with knee osteoarthritis were recruited and, of these, 168 were included and randomized into four groups with 42 each: interferential current, photobiomodulation, interferential current plus photobiomodulation or placebo groups. One hundred and sixty-four patients completed the study.
Patients received 12 sessions (three times a week) of treatment: 30 minutes of interferential current (active or placebo) followed by photobiomodulation (active or placebo).
Primary outcome: pain intensity at rest and during movement (numeric rating scale) after 12 sessions. Secondary outcomes: functional capacity (Timed Up & Go and Sit and Lift tests and Lequesne and WOMAC questionnaires), pressure pain threshold, conditioned pain modulation, and muscle strength production (isokinetic evaluation). Patients were assessed at baseline, after 12 sessions, and three and six months after the end of the treatment.
Interferential current plus photobiomodulation reduced pain intensity at rest and during movement compared to placebo and interferential current at all time points ( < 0.05). Photobiomodulation reduced pain intensity at rest compared to placebo at all time points ( < 0.05) and compared to interferential current at six months follow-up ( < 0.05). Photobiomodulation reduced pain intensity during movement compared to placebo at six months follow-up ( < 0.05).
Interferential current plus photobiomodulation or isolated photobiomodulation improve pain intensity in knee osteoarthritis.
评估干扰电流和光生物调节对膝骨关节炎患者的疗效。
随机、安慰剂对照、双盲临床试验。
圣保罗城市大学物理治疗诊所。
共招募了 184 名膝骨关节炎患者，其中 168 名符合条件并随机分为 4 组，每组 42 名：干扰电流组、光生物调节组、干扰电流加光生物调节组或安慰剂组。共有 164 名患者完成了研究。
患者接受 12 次治疗（每周 3 次）：30 分钟干扰电流（主动或安慰剂）后进行光生物调节（主动或安慰剂）。
主要结局：治疗 12 次后静息和运动时的疼痛强度（数字评分量表）。次要结局：功能能力（计时起立行走测试、坐起和提起测试、Lequesne 和 WOMAC 问卷）、压力疼痛阈值、条件性疼痛调制和肌肉力量产生（等速评估）。患者在基线、治疗 12 次后以及治疗结束后 3 个月和 6 个月进行评估。
干扰电流加光生物调节组在所有时间点（<0.05）均较安慰剂和干扰电流组静息和运动时疼痛强度降低；光生物调节组在所有时间点（<0.05）较安慰剂组静息时疼痛强度降低，且在治疗结束后 6 个月时与干扰电流组相比（<0.05）降低；光生物调节组在治疗结束后 6 个月时与安慰剂组相比，运动时疼痛强度降低（<0.05）。
干扰电流加光生物调节或单独的光生物调节均可改善膝骨关节炎的疼痛强度。
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