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汉黄芩素的叶片中分离得到的 3 种新化合物

Three new compounds from the leaves of Hance.

机构信息

Guangxi Key Laboratory of Functional Phytochemicals Research and Utilization, Guangxi Institute of Botany, Guangxi Zhuang Autonomous Region and Chinese Academy of Sciences, Guilin, China.

出版信息

Nat Prod Res. 2022 Oct;36(19):4906-4910. doi: 10.1080/14786419.2021.1910690. Epub 2021 Apr 24.

Abstract

Three new compounds (6,9)-6'-galloyl-roseoside (), purpurogallin ethyl carboxylate (), and tibetana A () were isolated from 80% methanol extract of the leaves of Hance. Their structures were elucidated based on comprehensive spectroscopic methods and chemical data, including optical rotation, UV, MS, 1 D and 2 D NMR spectra. Compounds and were evaluated for their -glucosidase inhibitory activity, pancreatic lipase inhibitory activity, and tyrosinase inhibitory activity.

摘要

从 的叶 80%甲醇提取物中分离得到了 3 个新化合物(6,9)-6′-没食子酰基蔷薇苷()、紫铆因乙酯()和藏红花 A()。基于全面的光谱方法和化学数据,包括旋光、UV、MS、1D 和 2D NMR 光谱,确定了它们的结构。对化合物 和 进行了 -葡萄糖苷酶抑制活性、胰脂肪酶抑制活性和酪氨酸酶抑制活性评价。

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