儿童混合性卵巢生殖细胞肿瘤：罕见关联病例报告
Mixed ovarian germ cell tumor in a child: A case report of a rare association.
作者信息
Benradi Larbi, El Haissoufi Kamal, Ammor Abdelouhab, Benmoussa Youssef, Kamaoui Imane, Haloui Anas, Bennani Amal, Benhaddou Houssain
机构信息
Uro-visceral and Genital Paediatric Surgery Department, Mohammed VI University Hospital, Oujda, Morocco.
Faculty of Medicine and Pharmacy, Mohammed Ist University, Oujda, Morocco.
出版信息
Ann Med Surg (Lond). 2021 Mar 29;65:102237. doi: 10.1016/j.amsu.2021.102237. eCollection 2021 May.
INTRODUCTION AND IMPORTANCE
ovarian tumors and especially mixed ovarian germ cell tumors are rarely seen in the paediatric population.
CASE PRESENTATION
we report the case of a 13-year-old girl which was successfully treated for a mixed ovarian germ cell tumor with a favorable evolution.
CLINICAL DISCUSSION
the incidence of mixed ovarian germ cell tumors, clinical manifestations, histologic distribution and prognosis are predominentely distinct in children and adolescents as compared to adult population. The diagnosis should be suspected in young girls with chronic abdominal pain and palpable swelling of the lower abdomen. Conservative surgery is the first therapeutic procedure that consists of a total resection of the mass with preservation of the reproductive function. Circulating tumor markers have the potential in diagnosis, prognostic stratification and for follow-up.
CONCLUSION
mixed ovarian germ cell tumors are uncommen in children. Their management must be multidisciplinary and conservative surgery by laparotomy represent the standard of care.
引言与重要性
卵巢肿瘤，尤其是混合性卵巢生殖细胞肿瘤在儿科人群中很少见。
病例报告
我们报告了一名13岁女孩的病例，她成功地接受了混合性卵巢生殖细胞肿瘤的治疗，病情进展良好。
临床讨论
与成人相比，儿童和青少年混合性卵巢生殖细胞肿瘤的发病率、临床表现、组织学分布和预后有明显差异。对于有慢性腹痛和下腹部可触及肿块的年轻女孩，应怀疑有该诊断。保守手术是首要的治疗方法，包括完整切除肿块并保留生殖功能。循环肿瘤标志物在诊断、预后分层和随访中具有潜力。
结论
混合性卵巢生殖细胞肿瘤在儿童中不常见。其治疗必须多学科进行，开腹的保守手术是标准治疗方法。
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