鞘内注射巴氯芬治疗相关感染：如何避免撤药？
-related intrathecal baclofen therapy infection: how to avoid withdrawal?
作者信息
De Larminat V, Zayet S, Klopfenstein T, Idelcadi M
机构信息
Pain Department, Nord Franche-Comté Hospital, Trevenans, France.
Infectious Diseases Department, Nord Franche-Comté Hospital, Trevenans, France.
出版信息
New Microbes New Infect. 2021 Mar 24;41:100875. doi: 10.1016/j.nmni.2021.100875. eCollection 2021 May.
Intrathecal baclofen therapy is commonly used for neurologically spastic patients. One of the major complications is hardware infection, which generally requires urgent removal of the pump and the intrathecal catheter, with the risk of severe baclofen withdrawal. We have recently been facing this situation and propose another solution with adapted antibiotic therapy, removal with immediate replacement of the intrathecal catheter, initially connected to an implanted port to continue baclofen administration. A new pump was secondarily implanted, after successful treatment of acute bacterial meningitis due to .
鞘内注射巴氯芬疗法常用于神经源性痉挛患者。主要并发症之一是硬件感染，这通常需要紧急取出泵和鞘内导管，存在严重巴氯芬戒断的风险。我们最近遇到了这种情况，并提出了另一种解决方案，即采用适应性抗生素治疗，取出鞘内导管后立即更换，最初连接到植入端口以继续给予巴氯芬。在成功治疗由……引起的急性细菌性脑膜炎后，二期植入了一个新泵。
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